4WHK
 
 | | A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1 | | Descriptor: | C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1 | | Authors: | Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S. | | Deposit date: | 2014-09-23 | | Release date: | 2014-12-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
|
|
4WHL
 | | A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1 | | Descriptor: | C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1 | | Authors: | Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S. | | Deposit date: | 2014-09-23 | | Release date: | 2014-12-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
|
|
4WHH
 | |
8WFP
 | | Crystal structure of polo-like kinase(PLK1)PBD in complex with DD-1 | | Descriptor: | DD-1, Serine/threonine-protein kinase PLK1 | | Authors: | Park, J, La, Y.K, Bang, J.K, Lee, S.J. | | Deposit date: | 2023-09-20 | | Release date: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer.
J.Med.Chem., 67, 2024
|
|
4N7Z
 | | Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep192 N-terminal fragment | | Descriptor: | Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4 | | Authors: | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | | Deposit date: | 2013-10-16 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
8H0G
 | | AQEE-30 in a HFIP solution | | Descriptor: | AQEE-30 | | Authors: | Park, O.-S, Jeon, Y.H, Cheong, C. | | Deposit date: | 2022-09-28 | | Release date: | 2022-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of AQEE-30 of VGF Neuropeptide in Membrane-Mimicking Environments.
Int J Mol Sci, 23, 2022
|
|
8H0U
 | | AQEE-30 in a DPC solution | | Descriptor: | AQEE-30 | | Authors: | Park, O.-S, Jeon, Y.H, Cheong, C. | | Deposit date: | 2022-09-30 | | Release date: | 2022-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of AQEE-30 of VGF Neuropeptide in Membrane-Mimicking Environments.
Int J Mol Sci, 23, 2022
|
|
6N45
 | |
6N46
 | |
5X3S
 | |
4RCP
 | | Crystal structure of Plk1 Polo-box domain in complex with PL-2 | | Descriptor: | 1,2-ETHANEDIOL, PL-2, Serine/threonine-protein kinase PLK1 | | Authors: | Lee, W.C, Song, J.H, Kim, H.Y. | | Deposit date: | 2014-09-16 | | Release date: | 2014-11-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1.
J.Med.Chem., 58, 2015
|
|
6CSV
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | Descriptor: | Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa | | Authors: | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | Deposit date: | 2018-03-21 | | Release date: | 2019-03-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
|
|
6CSU
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | Descriptor: | Centrosomal protein of 152 kDa, Centrosomal protein of 63 kDa | | Authors: | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | Deposit date: | 2018-03-21 | | Release date: | 2019-03-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
|
|
4N7V
 | | Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep152 N-terminal fragment | | Descriptor: | Centrosomal protein of 152 kDa, Serine/threonine-protein kinase PLK4 | | Authors: | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | | Deposit date: | 2013-10-16 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.758 Å) | | Cite: | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
4N9J
 | | Crystal structure of the cryptic polo box domain of human Plk4 | | Descriptor: | CHLORIDE ION, SULFATE ION, Serine/threonine-protein kinase PLK4 | | Authors: | Ku, B, Kim, J.H, Lee, K.S, Kim, S.J. | | Deposit date: | 2013-10-21 | | Release date: | 2014-07-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
5DMV
 | | Polo-box domain of Mouse Polo-like kinase 1 complexed with Emi2 (146-177) | | Descriptor: | F-box only protein 43, NICKEL (II) ION, Serine/threonine-protein kinase PLK1 | | Authors: | Namgoong, S. | | Deposit date: | 2015-09-09 | | Release date: | 2015-10-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Sci Rep, 5, 2015
|
|
5DMS
 | | Mouse Polo-box domain and Emi2 (169-177) | | Descriptor: | F-box only protein 43, Serine/threonine-protein kinase PLK1 | | Authors: | Namgoong, S. | | Deposit date: | 2015-09-09 | | Release date: | 2015-10-28 | | Method: | X-RAY DIFFRACTION (1.89999 Å) | | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Sci Rep, 5, 2015
|
|
5DNJ
 | | Mouse Polo-box domain and Peptide analog 702 | | Descriptor: | Serine/threonine-protein kinase PLK1, peptide 707-56A-SER-TPO-NH2 | | Authors: | Namgoong, S, Han, Y.H. | | Deposit date: | 2015-09-10 | | Release date: | 2016-02-24 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Sci Rep, 5, 2015
|
|
5CZY
 | | Crystal structure of LegAS4 | | Descriptor: | GLYCEROL, Legionella effector LegAS4, S-ADENOSYLMETHIONINE | | Authors: | Son, J, Hwang, K.Y, Lee, W.C. | | Deposit date: | 2015-08-01 | | Release date: | 2015-09-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4
Biochem.Biophys.Res.Commun., 465, 2015
|
|
3C5L
 | |
3HIH
 | |
3HIK
 | | Structure of human Plk1-PBD in complex with PLHSpT | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Pentamer phosphopeptide, ... | | Authors: | Wlodawer, A, Moulaei, T. | | Deposit date: | 2009-05-20 | | Release date: | 2009-06-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Nat.Struct.Mol.Biol., 16, 2009
|
|
3FVH
 | |
4HAB
 | | Crystal structure of Plk1 Polo-box domain in complex with PL-49 | | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION, PL-49, ... | | Authors: | Lee, W.C, Song, J.H, Kim, H.Y. | | Deposit date: | 2012-09-26 | | Release date: | 2013-04-03 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
Bioorg.Med.Chem., 21, 2013
|
|
4HY2
 | |
