3HIK

Structure of human Plk1-PBD in complex with PLHSpT

Summary for 3HIK

Entry DOI	10.2210/pdb3hik/pdb
Descriptor	Serine/threonine-protein kinase PLK1, Pentamer phosphopeptide, GLYCEROL, ... (5 entities in total)
Functional Keywords	kinase, serine/threonine protein kinase, cell cycle, localization, atp-binding, cell division, mitosis, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P53350
Total number of polymer chains	2
Total formula weight	28179.00
Authors	Wlodawer, A.,Moulaei, T. (deposition date: 2009-05-20, release date: 2009-06-09, Last modification date: 2017-11-01)
Primary citation	Yun, S.M.,Moulaei, T.,Lim, D.,Bang, J.K.,Park, J.E.,Shenoy, S.R.,Liu, F.,Kang, Y.H.,Liao, C.,Soung, N.K.,Lee, S.,Yoon, D.Y.,Lim, Y.,Lee, D.H.,Otaka, A.,Appella, E.,McMahon, J.B.,Nicklaus, M.C.,Burke, T.R.,Yaffe, M.B.,Wlodawer, A.,Lee, K.S. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat.Struct.Mol.Biol., 16:876-882, 2009 Cited by PubMed: 19597481 DOI: 10.1038/nsmb.1628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation