3HIH
Structure of human Plk1-PBD with glycerol and sulfate in the phophopeptide binding site
Summary for 3HIH
Entry DOI | 10.2210/pdb3hih/pdb |
Descriptor | Serine/threonine-protein kinase PLK1, SULFATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | kinase, phosphopeptide-binding domain, transferase, serine threonine protein kinase, atp-binding, cell cycle, cell division, mitosis, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P53350 |
Total number of polymer chains | 2 |
Total formula weight | 52691.85 |
Authors | Wlodawer, A.,Moulaei, T. (deposition date: 2009-05-20, release date: 2009-06-09, Last modification date: 2024-02-21) |
Primary citation | Yun, S.M.,Moulaei, T.,Lim, D.,Bang, J.K.,Park, J.E.,Shenoy, S.R.,Liu, F.,Kang, Y.H.,Liao, C.,Soung, N.K.,Lee, S.,Yoon, D.Y.,Lim, Y.,Lee, D.H.,Otaka, A.,Appella, E.,McMahon, J.B.,Nicklaus, M.C.,Burke, T.R.,Yaffe, M.B.,Wlodawer, A.,Lee, K.S. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat.Struct.Mol.Biol., 16:876-882, 2009 Cited by PubMed: 19597481DOI: 10.1038/nsmb.1628 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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