4R05
| Crystal structure of the refolded DENV3 methyltransferase | Descriptor: | Nonstructural protein NS5 | Authors: | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | Deposit date: | 2014-07-29 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Sci., 24, 2015
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8J36
| Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF00835231 | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | Authors: | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | Deposit date: | 2023-04-16 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
M49I mutant in complex with PF00835231 To Be Published
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6LXD
| Pri-miRNA bound DROSHA-DGCR8 complex | Descriptor: | Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ... | Authors: | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | Deposit date: | 2020-02-10 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Basis for pri-miRNA Recognition by Drosha. Mol.Cell, 78, 2020
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4E9B
| Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACTINONIN, COBALT (II) ION, ... | Authors: | Cui, K, Zhu, L, Lu, W, Huang, J. | Deposit date: | 2012-03-20 | Release date: | 2013-04-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification of Novel Peptide Deformylase Inhibitors from Natural Products To be Published
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5MV2
| Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus | Descriptor: | E protein | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | Deposit date: | 2017-01-14 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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6LXE
| DROSHA-DGCR8 complex | Descriptor: | Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION | Authors: | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | Deposit date: | 2020-02-10 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural Basis for pri-miRNA Recognition by Drosha. Mol.Cell, 78, 2020
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2LGX
| NMR structure for Kindle-2 N-terminus | Descriptor: | Fermitin family homolog 2 | Authors: | Perera, H.D, Ma, Y, Yang, J, Hirbawi, J, Plow, E.F, Qin, J. | Deposit date: | 2011-08-03 | Release date: | 2011-11-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation. Structure, 19, 2011
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3HIF
| The crystal structure of apo wild type CAP at 3.6 A resolution. | Descriptor: | Catabolite gene activator | Authors: | Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S. | Deposit date: | 2009-05-19 | Release date: | 2009-09-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding. Proc.Natl.Acad.Sci.USA, 106, 2009
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8WGF
| The Crystal Structure of JNK3 from Biortus. | Descriptor: | MAGNESIUM ION, Mitogen-activated protein kinase 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | Deposit date: | 2023-09-21 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Crystal Structure of JNK3 from Biortus. To Be Published
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8WGQ
| The Crystal Structure of L-asparaginase from Biortus. | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, L-asparaginase | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | Deposit date: | 2023-09-22 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of L-asparaginase from Biortus. To Be Published
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3HRO
| Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2) | Descriptor: | Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2) | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J. | Deposit date: | 2009-06-09 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proc.Natl.Acad.Sci.USA, 106, 2009
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7K65
| Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | Authors: | Zhang, Y, Bulkley, D.P, Liang, J, Manglik, A, Cheng, Y, Beachy, P.A. | Deposit date: | 2020-09-18 | Release date: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proc.Natl.Acad.Sci.USA, 117, 2020
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8SDU
| Structure of rat organic anion transporter 1 (OAT1) | Descriptor: | Solute carrier family 22 member 6 | Authors: | Dou, T, Jiang, J. | Deposit date: | 2023-04-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.05 Å) | Cite: | The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM. Nat.Struct.Mol.Biol., 30, 2023
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8SDZ
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7DR8
| Crystal structure of MERS-CoV 3CL protease in spacegroup P212121 | Descriptor: | 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2020-12-26 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.338149 Å) | Cite: | Crystal structure of MERS-CoV 3CL protease in spacegroup P212121 To Be Published
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8SDY
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3HRN
| crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2) | Descriptor: | Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2) | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J. | Deposit date: | 2009-06-09 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proc.Natl.Acad.Sci.USA, 106, 2009
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5G2X
| Structure a of Group II Intron Complexed with its Reverse Transcriptase | Descriptor: | 5'-R(*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*CP)-3', GROUP II INTRON, GROUP II INTRON-ENCODED PROTEIN LTRA | Authors: | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | Deposit date: | 2016-04-16 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of a Group II Intron in Complex with its Reverse Transcriptase. Nat.Struct.Mol.Biol., 23, 2016
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5G2Y
| Structure a of Group II Intron Complexed with its Reverse Transcriptase | Descriptor: | GROUP II INTRON | Authors: | Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W. | Deposit date: | 2016-04-16 | Release date: | 2016-05-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of a Group II Intron in Complex with its Reverse Transcriptase. Nat.Struct.Mol.Biol., 23, 2016
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4R0X
| Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | LeMaster, D.M, Mustafi, S.M, Brecher, M, Zhang, J, Heroux, A, Li, H.M, Hernandez, G. | Deposit date: | 2014-08-02 | Release date: | 2015-05-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. J.Biol.Chem., 290, 2015
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3IZJ
| Mm-cpn rls with ATP and AlFx | Descriptor: | Chaperonin | Authors: | Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J. | Deposit date: | 2010-10-29 | Release date: | 2011-02-02 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber. Cell(Cambridge,Mass.), 144, 2011
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5H0S
| EM Structure of VP1A and VP1B | Descriptor: | VP1 | Authors: | Li, X, Zhou, N, Xu, B, Chen, W, Zhu, B, Wang, X, Wang, J, Liu, H, Cheng, L. | Deposit date: | 2016-10-06 | Release date: | 2017-01-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Near-Atomic Resolution Structure Determination of a Cypovirus Capsid and Polymerase Complex Using Cryo-EM at 200kV J. Mol. Biol., 429, 2017
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4N0G
| Crystal Structure of PYL13-PP2CA complex | Descriptor: | Abscisic acid receptor PYL13, MAGNESIUM ION, Protein phosphatase 2C 37, ... | Authors: | Li, W, Wang, L, Sheng, X, Yan, C, Zhou, R, Hang, J, Yin, P, Yan, N. | Deposit date: | 2013-10-01 | Release date: | 2013-11-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13 Cell Res., 23, 2013
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4FGB
| Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form | Descriptor: | Calcium/calmodulin-dependent protein kinase type 1 | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | Deposit date: | 2012-06-04 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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7DVM
| DgkA structure in E.coli lipid bilayer | Descriptor: | Diacylglycerol kinase | Authors: | Li, J, Yang, J. | Deposit date: | 2021-01-13 | Release date: | 2022-04-13 | Last modified: | 2023-09-27 | Method: | SOLID-STATE NMR | Cite: | Structure of membrane diacylglycerol kinase in lipid bilayers. Commun Biol, 4, 2021
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