4R05

Crystal structure of the refolded DENV3 methyltransferase

Summary for 4R05

DescriptorNonstructural protein NS5 (2 entities in total)
Functional Keywordsmethyltransferase, flavivirus, transferase
Biological sourceDengue virus 3
Total number of polymer chains2
Total molecular weight60139.17
Authors
Brecher, M.B.,Li, Z.,Zhang, J.,Chen, H.,Lin, Q.,Liu, B.,Li, H.M. (deposition date: 2014-07-29, release date: 2014-11-12, Last modification date: 2015-01-21)
Primary citation
Brecher, M.B.,Li, Z.,Zhang, J.,Chen, H.,Lin, Q.,Liu, B.,Li, H.
Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24:117-128, 2015
PubMed: 25352331 (PDB entries with the same primary citation)
DOI: 10.1002/pro.2594
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.310700.2%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4r05
no rotation
Molmil generated image of 4r05
rotated about x axis by 90°
Molmil generated image of 4r05
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 4r05
no rotation
Molmil generated image of 4r05
rotated about x axis by 90°
Molmil generated image of 4r05
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4r05.pdb2.gz [45.17 KB])
Coordinate files for Biological unit (4r05.pdb1.gz [45.31 KB])
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