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3P4L
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BU of 3p4l by Molmil
Crystal structure of a hemojuvelin-binding fragment of neogenin
Descriptor: Neogenin
Authors:Yang, F, West Jr, A.P, Bjorkman, P.J.
Deposit date:2010-10-06
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8A.
J.Struct.Biol., 174, 2011
7MXE
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BU of 7mxe by Molmil
Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ...
Authors:Abernathy, M.E, Bjorkman, P.J.
Deposit date:2021-05-19
Release date:2021-10-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.
Npj Vaccines, 6, 2021
4NHH
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BU of 4nhh by Molmil
Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
4Q6Y
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BU of 4q6y by Molmil
Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
Deposit date:2014-04-23
Release date:2014-07-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q74
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BU of 4q74 by Molmil
F241A Fc
Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
Deposit date:2014-04-24
Release date:2014-07-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4P9M
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BU of 4p9m by Molmil
Crystal structure of 8ANC195 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4Q7D
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BU of 4q7d by Molmil
Wild type Fc (wtFc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
Deposit date:2014-04-24
Release date:2014-07-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4P9H
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BU of 4p9h by Molmil
Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4NHG
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BU of 4nhg by Molmil
Crystal Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (8.001 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
6CH7
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BU of 6ch7 by Molmil
XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH8
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BU of 6ch8 by Molmil
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, 35O22 Light Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CM3
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BU of 6cm3 by Molmil
BG505 SOSIP in complex with sCD4, 17b, 8ANC195
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2018-03-02
Release date:2018-10-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
6CHB
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BU of 6chb by Molmil
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and IOMA
Descriptor: BG18 Heavy Chain, BG18 Light Chain, Envelope glycoprotein gp120, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6.801 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
4FQ1
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BU of 4fq1 by Molmil
Crystal Structure of PGT121 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2012-06-24
Release date:2012-11-14
Last modified:2021-05-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FQC
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BU of 4fqc by Molmil
Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan
Descriptor: Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2012-06-25
Release date:2012-11-14
Last modified:2021-05-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FQQ
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BU of 4fqq by Molmil
Crystal Structure of Germline Antibody PGT121-GL Fab
Descriptor: Fab heavy chain, Fab light chain, SODIUM ION
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2012-06-25
Release date:2012-11-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
6CH9
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BU of 6ch9 by Molmil
Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.85 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
4GW4
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BU of 4gw4 by Molmil
Crystal structure of 3BNC60 Fab with P61A mutation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC60 Fab Heavy-chain, 3BNC60 Fab Light-chain
Authors:Diskin, R, Fu, B.Z, Bjorkman, P.J.
Deposit date:2012-08-31
Release date:2013-04-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
6DFJ
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BU of 6dfj by Molmil
Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII
Descriptor: Dengue 1 Envelope DIII domain, anti-Zika antibody Z021, Heavy Chain, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2018-05-14
Release date:2018-10-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018
6DFI
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BU of 6dfi by Molmil
Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII
Descriptor: Zika virus envelope protein DIII, anti-Zika antibody Z021, Heavy Chain, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2018-05-14
Release date:2018-10-24
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018
4FQ2
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BU of 4fq2 by Molmil
Crystal Structure of 10-1074 Fab
Descriptor: 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2012-06-24
Release date:2012-11-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
5CAY
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BU of 5cay by Molmil
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
Authors:Davenport, Y.W, Bjorkman, P.J.
Deposit date:2015-06-30
Release date:2015-12-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
5CJX
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BU of 5cjx by Molmil
Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 heavy chain, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-07-15
Release date:2015-09-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.584 Å)
Cite:Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5D6D
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BU of 5d6d by Molmil
Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, ...
Authors:Ahmed, A.A, Bjorkman, P.J.
Deposit date:2015-08-12
Release date:2016-02-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
5D4Q
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BU of 5d4q by Molmil
Crystal structure of GASDALIE IgG1 Fc
Descriptor: Ig gamma-1 chain C region, alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ahmed, A.A, Bjorkman, P.J.
Deposit date:2015-08-08
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016

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