5D6D

Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa

Summary for 5D6D

Entry DOI	10.2210/pdb5d6d/pdb
Descriptor	Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	adcc, immune system, igg
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	87009.70
Authors	Ahmed, A.A.,Bjorkman, P.J. (deposition date: 2015-08-12, release date: 2016-02-10, Last modification date: 2023-09-27)
Primary citation	Ahmed, A.A.,Keremane, S.R.,Vielmetter, J.,Bjorkman, P.J. Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa. J.Struct.Biol., 194:78-89, 2016 Cited by PubMed: 26850169 DOI: 10.1016/j.jsb.2016.02.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.13 Å)

Structure validation