7RPV
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1MIC
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6KOR
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![BU of 6kor by Molmil](/molmil-images/mine/6kor) | Crystal structure of the RRM domain of SYNCRIP | 分子名称: | Heterogeneous nuclear ribonucleoprotein Q | 著者 | Chen, Y, Chan, J, Chen, W, Jobichen, C. | 登録日 | 2019-08-12 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | SYNCRIP, a new player in pri-let-7a processing. Rna, 26, 2020
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4V90
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![BU of 4v90 by Molmil](/molmil-images/mine/4v90) | Thermus thermophilus Ribosome | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. | 登録日 | 2014-02-22 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of EF-G-ribosome complex in a pretranslocation state. Nat. Struct. Mol. Biol., 20, 2013
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6DWS
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![BU of 6dws by Molmil](/molmil-images/mine/6dws) | Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | 分子名称: | 8-{[(2-chlorophenyl)methyl]amino}adenosine, Endoplasmic reticulum chaperone BiP, MAGNESIUM ION | 著者 | Chen, Y, Antoshchenko, T, Smil, D, Zepeda, C, Huang, Y, Park, H.W. | 登録日 | 2018-06-27 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol To Be Published
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7AX1
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6EBV
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![BU of 6ebv by Molmil](/molmil-images/mine/6ebv) | Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N7-Pan | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, N-heptyl-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Type II pantothenate kinase | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H, Park, H. | 登録日 | 2018-08-07 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase. To Be Published
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6KI3
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![BU of 6ki3 by Molmil](/molmil-images/mine/6ki3) | The crystal structure of AsfvAP:dF commplex | 分子名称: | DNA (5'-D(*CP*CP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*CP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*GP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*AP*G)-3'), ... | 著者 | Chen, Y, Gan, J. | 登録日 | 2019-07-17 | 公開日 | 2020-05-27 | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | 主引用文献 | A unique DNA-binding mode of African swine fever virus AP endonuclease. Cell Discov, 6, 2020
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4CRU
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![BU of 4cru by Molmil](/molmil-images/mine/4cru) | Complex of human CNOT9 and CNOT1 including one tryptophan | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | 登録日 | 2014-03-01 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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4CRW
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![BU of 4crw by Molmil](/molmil-images/mine/4crw) | Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G) | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | 登録日 | 2014-03-01 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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7YK6
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![BU of 7yk6 by Molmil](/molmil-images/mine/7yk6) | Cryo-EM structure of the compound 4-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | 分子名称: | 1-[2-(4-chlorophenyl)ethyl]-3-[(7-ethyl-5-oxidanyl-1H-indol-3-yl)methylideneamino]guanidine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | 登録日 | 2022-07-21 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14, 2023
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7YJ4
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![BU of 7yj4 by Molmil](/molmil-images/mine/7yj4) | Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | 登録日 | 2022-07-19 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14, 2023
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7YK7
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![BU of 7yk7 by Molmil](/molmil-images/mine/7yk7) | Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Xu, H.E, Yang, D.H, Liu, H, Wang, M.W. | 登録日 | 2022-07-21 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14, 2023
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4WK8
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![BU of 4wk8 by Molmil](/molmil-images/mine/4wk8) | FOXP3 forms a domain-swapped dimer to bridge DNA | 分子名称: | DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), Forkhead box protein P3 | 著者 | Chen, Y, Chen, L. | 登録日 | 2014-10-01 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | 主引用文献 | DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Nucleic Acids Res., 43, 2015
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6R80
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![BU of 6r80 by Molmil](/molmil-images/mine/6r80) | Structure of AFF4 C-terminal homology domain | 分子名称: | AF4/FMR2 family member 4 | 著者 | Chen, Y, Cramer, P. | 登録日 | 2019-03-30 | 公開日 | 2019-06-12 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. J.Biol.Chem., 294, 2019
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7OKX
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![BU of 7okx by Molmil](/molmil-images/mine/7okx) | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | 登録日 | 2021-05-18 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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7OKY
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![BU of 7oky by Molmil](/molmil-images/mine/7oky) | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | 登録日 | 2021-05-18 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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7OL0
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![BU of 7ol0 by Molmil](/molmil-images/mine/7ol0) | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | 登録日 | 2021-05-18 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
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6KZW
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![BU of 6kzw by Molmil](/molmil-images/mine/6kzw) | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum | 分子名称: | PHOSPHATE ION, Pyridoxal phosphate homeostasis protein | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | 登録日 | 2019-09-25 | 公開日 | 2019-10-16 | 最終更新日 | 2021-01-13 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum To Be Published
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1J48
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![BU of 1j48 by Molmil](/molmil-images/mine/1j48) | Crystal Structure of Apo-C1027 | 分子名称: | Apoprotein of C1027 | 著者 | Chen, Y, Li, J, Liu, Y, Bartlam, M, Gao, Y, Jin, L, Tang, H, Shao, Y, Zhen, Y, Rao, Z. | 登録日 | 2001-07-30 | 公開日 | 2003-06-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex To be published
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1CZ8
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![BU of 1cz8 by Molmil](/molmil-images/mine/1cz8) | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY | 分子名称: | HEAVY CHAIN OF NEUTRALIZING ANTIBODY, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, SULFATE ION, ... | 著者 | Chen, Y, Wiesmann, C, Fuh, G, Li, B, Christinger, H.W, McKay, P, de Vos, A.M, Lowman, H.B. | 登録日 | 1999-09-01 | 公開日 | 2000-03-20 | 最終更新日 | 2017-04-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen. J.Mol.Biol., 293, 1999
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2XEX
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![BU of 2xex by Molmil](/molmil-images/mine/2xex) | crystal structure of Staphylococcus aureus elongation factor G | 分子名称: | CHLORIDE ION, ELONGATION FACTOR G, POTASSIUM ION | 著者 | Chen, Y, Koripella, R.K, Sanyal, S, Selmer, M. | 登録日 | 2010-05-19 | 公開日 | 2010-07-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Staphylococcus Aureus Elongation Factor G - Structure and Analysis of a Target for Fusidic Acid. FEBS J., 277, 2010
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7BVD
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![BU of 7bvd by Molmil](/molmil-images/mine/7bvd) | Anthranilate synthase component I (TrpE)[Mycolicibacterium smegmatis] | 分子名称: | Anthranilate synthase component 1, BENZOIC ACID, GLYCEROL, ... | 著者 | Chen, Y, Che, S, Zhang, Q, Bartlam, M. | 登録日 | 2020-04-10 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of subunit I of the anthranilate synthase complex of Mycolicibacterium smegmatis Biochem.Biophys.Res.Commun., 527, 2020
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8DKS
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![BU of 8dks by Molmil](/molmil-images/mine/8dks) | IRAK4 IN COMPLEX WITH COMPOUND #3 | 分子名称: | (1S,2S,3R,4R)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide, BETA-MERCAPTOETHANOL, Interleukin-1 receptor-associated kinase 4 | 著者 | Chen, Y, Lin, N. | 登録日 | 2022-07-06 | 公開日 | 2022-08-03 | 最終更新日 | 2022-08-17 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Bicyclic pyrimidine compounds as potent IRAK4 inhibitors. Bioorg.Med.Chem.Lett., 73, 2022
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4HJE
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![BU of 4hje by Molmil](/molmil-images/mine/4hje) | Crystal structure of p53 core domain in complex with DNA | 分子名称: | Cellular tumor antigen p53, DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), ... | 著者 | Chen, Y, Chen, L. | 登録日 | 2012-10-12 | 公開日 | 2013-07-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.907 Å) | 主引用文献 | Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion. Nucleic Acids Res., 41, 2013
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