7OL0

Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)

Summary for 7OL0

• Entry DOI: 10.2210/pdb7ol0/pdb
• Related: 7OKX 7OKY
• EMDB information: 12966 12967 12968 12969 12970 12971 12972 12973 12974
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA_pol_L_2 domain-containing protein, ... (18 entities in total)
• Functional Keywords: pol ii, super elongation complex, ell2, eaf1, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 16
• Total formula weight: 696776.74

Authors

Chen, Y.,Vos, S.M.,Dienemann, C.,Ninov, M.,Urlaub, H.,Cramer, P. (deposition date: 2021-05-18, release date: 2021-07-14, Last modification date: 2021-09-01)

• Primary citation: Chen, Y.,Vos, S.M.,Dienemann, C.,Ninov, M.,Urlaub, H.,Cramer, P.; Allosteric transcription stimulation by RNA polymerase II super elongation complex.; Mol.Cell, 81:3386-3399.e10, 2021; PubMed: 34265249; DOI: 10.1016/j.molcel.2021.06.019

Experimental method

ELECTRON MICROSCOPY (3 Å)