7OKX

Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure)

Summary for 7OKX

Entry DOI	10.2210/pdb7okx/pdb
Related	7OKX 7OKY 7OL0
EMDB information	12966 12967 12968 12969 12970 12971 12972 12973 12974
Descriptor	DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA_pol_L_2 domain-containing protein, ... (20 entities in total)
Functional Keywords	pol ii, super elongation complex, ell2, eaf1, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	18
Total formula weight	798288.07
Authors	Chen, Y.,Vos, S.M.,Dienemann, C.,Ninov, M.,Urlaub, H.,Cramer, P. (deposition date: 2021-05-18, release date: 2021-07-14, Last modification date: 2021-09-01)
Primary citation	Chen, Y.,Vos, S.M.,Dienemann, C.,Ninov, M.,Urlaub, H.,Cramer, P. Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81:3386-3399.e10, 2021 Cited by PubMed: 34265249 DOI: 10.1016/j.molcel.2021.06.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation