7OKX
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1970 | 217450.1 | 1 | UniProt (P11414) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) UniProt (by SIFTS) (A0A7M4DUC2) | Sus scrofa (Pig) | |
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1251 | 142426.1 | 1 | UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Sus scrofa (Pig) | |
| 3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) | Sus scrofa (Pig) | |
| 4 | D (D) | RNA polymerase II subunit D | polymer | 184 | 20962.6 | 1 | UniProt (A0A287ADR4) Pfam (PF03874) | Sus scrofa (Pig) | |
| 5 | E (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) | Sus scrofa (Pig) | RPB5 homolog |
| 6 | F (F) | DNA-directed RNA polymerase II subunit F | polymer | 127 | 14477.0 | 1 | UniProt (F1SKN8) Pfam (PF01192) UniProt (by SIFTS) (A0A4X1VEK9) | Sus scrofa (Pig) | DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog |
| 7 | G (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (I3LJZ9) | Sus scrofa (Pig) | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (A0A4X1ULF2) Pfam (PF03870) UniProt (by SIFTS) (I3LCB2) | Sus scrofa (Pig) | |
| 9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) | Sus scrofa (Pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 10 | J (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A4X1VYD0) Pfam (PF01194) | Sus scrofa (Pig) | |
| 11 | K (K) | RNA_pol_L_2 domain-containing protein | polymer | 117 | 13310.3 | 1 | UniProt (A0A4X1UK25) Pfam (PF13656) UniProt (by SIFTS) (F1RKE4) | Sus scrofa (Pig) | |
| 12 | L (L) | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (I3LN51) Pfam (PF03604) UniProt (by SIFTS) (A0A4X1TRS6) | Sus scrofa (Pig) | |
| 13 | M (M) | RNA polymerase II elongation factor ELL2 | polymer | 640 | 72435.4 | 1 | UniProt (O00472) Pfam (PF10390) Pfam (PF07303) | Homo sapiens (Human) | |
| 14 | N (N) | Non-template DNA | polymer | 48 | 14672.4 | 1 | HIV whole-genome vector AA1305#18 | ||
| 15 | O (O) | ELL-associated factor 1 | polymer | 268 | 29075.9 | 1 | UniProt (Q96JC9) Pfam (PF09816) | Homo sapiens (Human) | |
| 16 | P (P) | RNA | polymer | 47 | 15076.0 | 1 | HIV whole-genome vector AA1305#18 | ||
| 17 | Q (T) | Template DNA | polymer | 48 | 14934.6 | 1 | HIV whole-genome vector AA1305#18 | ||
| 18 | R (Z) | Transcription elongation factor SPT5 | polymer | 1087 | 121145.5 | 1 | UniProt (O00267) Pfam (PF11942) Pfam (PF03439) Pfam (PF00467) | Homo sapiens (Human) | hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein |
| 19 | S (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 20 | AA, T, U, V, W... (L, A, B, C, I...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 797740.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 798288.1 |
