6DWS

Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Summary for 6DWS

• Entry DOI: 10.2210/pdb6dws/pdb
• Descriptor: Endoplasmic reticulum chaperone BiP, 8-{[(2-chlorophenyl)methyl]amino}adenosine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: human grp78, adenosine analog, chaperone, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 85173.69

Authors

Chen, Y.,Antoshchenko, T.,Smil, D.,Zepeda, C.,Huang, Y.,Park, H.W. (deposition date: 2018-06-27, release date: 2019-07-03, Last modification date: 2024-03-13)

• Primary citation: Chen, Y.,Antoshchenko, T.,Smil, D.,Zepeda, C.,Huang, Y.,Park, H.W.; Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)