6DWS

Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Endoplasmic reticulum chaperone BiP	polymer	382	42155.7	2	UniProt (P11021) Pfam (PF00012)	Homo sapiens (Human)	78 kDa glucose-regulated protein,GRP-78,Binding-immunoglobulin protein,BiP,Heat shock protein 70 family protein 5,HSP70 family protein 5,Heat shock protein family A member 5,Immunoglobulin heavy chain-binding protein
2	C, E (A, B)	8-{[(2-chlorophenyl)methyl]amino}adenosine	non-polymer		406.8	2	Chemie (HFY)
3	D, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H (A, B)	water	water		18.0	313	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84311.4
Non-Polymers*	Number of molecules	4
	Total formula weight	862.3
All*	Total formula weight	85173.7

*Water molecules are not included.