4CRU

Complex of human CNOT9 and CNOT1 including one tryptophan

Summary for 4CRU

• Entry DOI: 10.2210/pdb4cru/pdb
• Related: 2FV2 4CRV
• Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ... (4 entities in total)
• Functional Keywords: gene regulation, tnrc6 binding, mirisc, mrna silencing, mrna deadenylation, argonaute, transcription
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm, P-body: A5YKK6; Nucleus (By similarity): Q92600
• Total number of polymer chains: 2
• Total formula weight: 60430.98

Authors

Chen, Y.,Boland, A.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-03-01, release date: 2014-05-07, Last modification date: 2023-12-20)

• Primary citation: Chen, Y.,Boland, A.,Kuzuoglu-Ozturk, D.,Bawankar, P.,Loh, B.,Chang, C.T.,Weichenrieder, O.,Izaurralde, E.; A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing; Mol.Cell, 54:737-, 2014; PubMed: 24768540; DOI: 10.1016/J.MOLCEL.2014.03.034

Experimental method

X-RAY DIFFRACTION (1.65 Å)