1T0M
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![BU of 1t0m by Molmil](/molmil-images/mine/1t0m) | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | 著者 | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | 登録日 | 2004-04-12 | 公開日 | 2004-11-23 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
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1T0N
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![BU of 1t0n by Molmil](/molmil-images/mine/1t0n) | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | 著者 | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | 登録日 | 2004-04-12 | 公開日 | 2004-11-23 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
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1S9X
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![BU of 1s9x by Molmil](/molmil-images/mine/1s9x) | Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQA, in complex with HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | 登録日 | 2004-02-05 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
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1S9Y
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![BU of 1s9y by Molmil](/molmil-images/mine/1s9y) | Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQS, in complex with HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | 登録日 | 2004-02-05 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
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1S9W
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![BU of 1s9w by Molmil](/molmil-images/mine/1s9w) | Crystal Structure Analysis of NY-ESO-1 epitope, SLLMWITQC, in complex with HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | 登録日 | 2004-02-05 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
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1YN7
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![BU of 1yn7 by Molmil](/molmil-images/mine/1yn7) | Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase | 分子名称: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | 登録日 | 2005-01-24 | 公開日 | 2005-06-28 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
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1YN6
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![BU of 1yn6 by Molmil](/molmil-images/mine/1yn6) | Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase | 分子名称: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | 登録日 | 2005-01-23 | 公開日 | 2005-06-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
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3BUY
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![BU of 3buy by Molmil](/molmil-images/mine/3buy) | MHC-I in complex with peptide | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | 著者 | Rossjohn, J, La Gruta, N.L, Purcell, A.W, Turner, S.J, Dunstone, M.A. | 登録日 | 2008-01-03 | 公開日 | 2008-03-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides Proc.Natl.Acad.Sci.Usa, 105, 2008
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6VWH
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![BU of 6vwh by Molmil](/molmil-images/mine/6vwh) | |
6VWG
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![BU of 6vwg by Molmil](/molmil-images/mine/6vwg) | Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | 著者 | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | 登録日 | 2020-02-19 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
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6VWJ
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![BU of 6vwj by Molmil](/molmil-images/mine/6vwj) | |
4PG2
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![BU of 4pg2 by Molmil](/molmil-images/mine/4pg2) | |
6MWR
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![BU of 6mwr by Molmil](/molmil-images/mine/6mwr) | Recognition of MHC-like molecule | 分子名称: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Le Nours, J, Rossjohn, J. | 登録日 | 2018-10-30 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A class of gamma delta T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science, 366, 2019
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6MPV
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6N64
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![BU of 6n64 by Molmil](/molmil-images/mine/6n64) | Crystal structure of mouse SMCHD1 hinge domain | 分子名称: | Structural maintenance of chromosomes flexible hinge domain-containing protein 1, Uncharacterized peptide from Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | 著者 | Birkinshaw, R.W, Chen, K, Czabotar, P.E, Blewitt, M.E, Murphy, J.M. | 登録日 | 2018-11-25 | 公開日 | 2020-06-17 | 最終更新日 | 2021-01-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues. Sci.Signal., 13, 2020
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6EB6
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![BU of 6eb6 by Molmil](/molmil-images/mine/6eb6) | Crystal structure of BAX W139A monomer | 分子名称: | Apoptosis regulator BAX, FORMIC ACID | 著者 | Robin, A.Y. | 登録日 | 2018-08-05 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.023 Å) | 主引用文献 | BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association. Cell Rep, 27, 2019
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6MCY
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![BU of 6mcy by Molmil](/molmil-images/mine/6mcy) | Crystal structure of mouse Bak | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, FORMIC ACID | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M. | 登録日 | 2018-09-03 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.748 Å) | 主引用文献 | A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis. Nat.Chem.Biol., 15, 2019
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7JW7
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![BU of 7jw7 by Molmil](/molmil-images/mine/7jw7) | Structure of monobody 27 human MLKL pseudokinase domain complex | 分子名称: | Mixed lineage kinase domain-like protein, Monobody 27 | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | 登録日 | 2020-08-25 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12, 2021
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7JXU
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![BU of 7jxu by Molmil](/molmil-images/mine/7jxu) | Structure of monobody 32 human MLKL pseudokinase domain complex | 分子名称: | 1,2-ETHANEDIOL, Mixed lineage kinase domain-like protein, Monobody 32 | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | 登録日 | 2020-08-28 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12, 2021
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2ZOK
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![BU of 2zok by Molmil](/molmil-images/mine/2zok) | Crystal structure of H-2Db in complex with JHMV epitope S510 | 分子名称: | 9-meric peptide from Spike glycoprotein, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Theodossis, A, Dunstone, M.A, Rossjohn, J. | 登録日 | 2008-05-22 | 公開日 | 2008-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biological basis of CTL escape in coronavirus-infected mice. J Immunol., 180, 2008
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2ZSW
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![BU of 2zsw by Molmil](/molmil-images/mine/2zsw) | Crystal structure of H-2Kb in complex with the Q600Y variant of JHMV epitope S598 | 分子名称: | 8-mer peptide from spike glycoprotein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Theodossis, A, Dunstone, M.A, Rossjohn, J. | 登録日 | 2008-09-18 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. Plos Pathog., 4, 2008
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2ZSV
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![BU of 2zsv by Molmil](/molmil-images/mine/2zsv) | Crystal structure of H-2Kb in complex with JHMV epitope S598 | 分子名称: | 8-mer peptide from spike glycoprotein, Beta-2-microglobulin, CYSTEINE, ... | 著者 | Theodossis, A, Dunstone, M.A, Rossjohn, J. | 登録日 | 2008-09-18 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. Plos Pathog., 4, 2008
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2ZOL
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![BU of 2zol by Molmil](/molmil-images/mine/2zol) | Crystal structure of H-2Db in complex with the W513S variant of JHMV epitope S510 | 分子名称: | 9-meric peptide from Spike glycoprotein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Theodossis, A, Dunstone, M.A, Rossjohn, J. | 登録日 | 2008-05-22 | 公開日 | 2008-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and biological basis of CTL escape in coronavirus-infected mice. J Immunol., 180, 2008
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3L3K
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![BU of 3l3k by Molmil](/molmil-images/mine/3l3k) | Crystal structure of HLA-B*4402 in complex with the R5A/F7A double mutant of a self-peptide derived from DPA*0201 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Theodossis, A, Ely, L.K, Rossjohn, J. | 登録日 | 2009-12-17 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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3L3H
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![BU of 3l3h by Molmil](/molmil-images/mine/3l3h) | X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC | 分子名称: | 10-mer peptide from Polymerase acidic protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Welland, A, Clements, C.S, Dunstone, M.A, Rossjohn, J. | 登録日 | 2009-12-17 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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