6MPV

Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex

Summary for 6MPV

EMDB information9192
DescriptorCysteine-rich protective antigen, Reticulocyte binding protein 5, PfRipr, ... (4 entities in total)
Functional Keywordsinvasion ligand protein complex, cell invasion
Biological sourcePlasmodium falciparum (isolate 3D7)
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Total number of polymer chains4
Total molecular weight80896.8
Authors
Wilson, W.,Zhiheng, Y.,Cowman, A.F. (deposition date: 2018-10-08, release date: 2018-12-12, Last modification date: 2019-01-16)
Primary citation
Wong, W.,Huang, R.,Menant, S.,Hong, C.,Sandow, J.J.,Birkinshaw, R.W.,Healer, J.,Hodder, A.N.,Kanjee, U.,Tonkin, C.J.,Heckmann, D.,Soroka, V.,Sogaard, T.M.M.,Jorgensen, T.,Duraisingh, M.T.,Czabotar, P.E.,de Jongh, W.A.,Tham, W.H.,Webb, A.I.,Yu, Z.,Cowman, A.F.
Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.
Nature, 565:118-121, 2019
PubMed: 30542156 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0779-6
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers180 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures