1YN7

Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase

Summary for 1YN7

Related1YN6
DescriptorH-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, 10-mer peptide from RNA-directed RNA polymerase subunit P2, ... (4 entities in total)
Functional Keywordsmhc class 1, h2-db, influenza a, peptide of acid polymerase, immune system
Biological sourceMus musculus (house mouse)
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Cellular locationMembrane; Single-pass type I membrane protein P01899
Secreted P01887
Total number of polymer chains3
Total molecular weight44740.15
Authors
Turner, S.J.,Kedzierska, K.,Komodromou, H.,La Gruta, N.L.,Dunstone, M.A.,Webb, A.I.,Webby, R.,Walden, H.,Xie, W.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C. (deposition date: 2005-01-24, release date: 2005-06-28, Last modification date: 2011-07-13)
Primary citation
Turner, S.J.,Kedzierska, K.,Komodromou, H.,La Gruta, N.L.,Dunstone, M.A.,Webb, A.I.,Webby, R.,Walden, H.,Xie, W.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C.
Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6:382-389, 2005
PubMed: 15785764 (PDB entries with the same primary citation)
DOI: 10.1038/ni1175
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers130.5%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution