1T0N

Conformational switch in polymorphic H-2K molecules containing an HSV peptide

Summary for 1T0N

• Entry DOI: 10.2210/pdb1t0n/pdb
• Related: 1T0M
• Descriptor: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Glycoprotein B, ... (4 entities in total)
• Functional Keywords: immunoglobulin domain, mhc class i alpha domains, hsv peptide, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 89238.25

Authors

Webb, A.I.,Borg, N.A.,Dunstone, M.A.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Carbone, F.R.,Bottomley, S.P.,Purcell, A.W.,Rossjohn, J. (deposition date: 2004-04-12, release date: 2004-11-23, Last modification date: 2019-11-06)

• Primary citation: Webb, A.I.,Borg, N.A.,Dunstone, M.A.,Kjer-Nielsen, L.,Beddoe, T.,McCluskey, J.,Carbone, F.R.,Bottomley, S.P.,Aguilar, M.I.,Purcell, A.W.,Rossjohn, J.; The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.; J Immunol., 173:402-409, 2004; PubMed: 15210799; DOI: 10.4049/jimmunol.173.1.402

Experimental method

X-RAY DIFFRACTION (1.8 Å)