7JW7
Structure of monobody 27 human MLKL pseudokinase domain complex
Summary for 7JW7
| Entry DOI | 10.2210/pdb7jw7/pdb |
| Descriptor | Mixed lineage kinase domain-like protein, Monobody 27 (3 entities in total) |
| Functional Keywords | pseudokinase, monobody, complex, necroptosis, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 43403.42 |
| Authors | Meng, Y.,Garnish, S.E.,Koide, A.,Koide, S.,Czabotar, P.E.,Murphy, J.M. (deposition date: 2020-08-25, release date: 2021-03-10, Last modification date: 2023-10-18) |
| Primary citation | Garnish, S.E.,Meng, Y.,Koide, A.,Sandow, J.J.,Denbaum, E.,Jacobsen, A.V.,Yeung, W.,Samson, A.L.,Horne, C.R.,Fitzgibbon, C.,Young, S.N.,Smith, P.P.C.,Webb, A.I.,Petrie, E.J.,Hildebrand, J.M.,Kannan, N.,Czabotar, P.E.,Koide, S.,Murphy, J.M. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12:2211-2211, 2021 Cited by PubMed: 33850121DOI: 10.1038/s41467-021-22400-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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