3IGC
 
 | | Smallpox virus topoisomerase-DNA transition state | | 分子名称: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | | 著者 | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2009-07-27 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.
Structure, 18, 2010
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1MW9
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1MW8
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2H7G
 | | Structure of variola topoisomerase non-covalently bound to DNA | | 分子名称: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 | | 著者 | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2006-06-02 | | 公開日 | 2006-08-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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2H7F
 | | Structure of variola topoisomerase covalently bound to DNA | | 分子名称: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', DNA topoisomerase 1 | | 著者 | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2006-06-02 | | 公開日 | 2006-08-15 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
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7C0Q
 | | a Legionella pneumophila effector Lpg2505 | | 分子名称: | GLYCEROL, effector Lpg2505 | | 著者 | Chen, T.T, Han, A.D, Luo, Z.Q, McCloskey, A, Perri, K. | | 登録日 | 2020-05-01 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The metaeffector MesI regulates the activity of the Legionella effector SidI through direct protein-protein interactions.
Microbes Infect., 23, 2021
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4LO6
 | | HA70-alpha2,6-SiaLC | | 分子名称: | CHLORIDE ION, HA-70, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | | 著者 | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | | 登録日 | 2013-07-12 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
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4LO7
 | | HA70(D3)-HA17-HA33 | | 分子名称: | HA-17, HA-33, HA-70 | | 著者 | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | | 登録日 | 2013-07-12 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.73 Å) | | 主引用文献 | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
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4E1H
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4LO8
 | | HA70(D3)-HA17 | | 分子名称: | HA-17, HA-70 | | 著者 | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | | 登録日 | 2013-07-12 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
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4M1B
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8UIQ
 | | H47Q NicC with 2-mercaptopyridine ligand | | 分子名称: | 2-PYRIDINETHIOL, 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hicks, K.A, Perry, K, Turlington, Z.R, Vaz Ferreira de Macedo, S. | | 登録日 | 2023-10-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
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8UIV
 | | H47Q NicC with bound FAD | | 分子名称: | 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hicks, K.A, Perry, K. | | 登録日 | 2023-10-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | | 主引用文献 | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
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5JMC
 | | Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C | | 分子名称: | Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C | | 著者 | Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. | | 登録日 | 2016-04-28 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
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5JLV
 | | Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. | | 登録日 | 2016-04-27 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
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8VRR
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8VRS
 | | Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody | | 分子名称: | 4H11 scFv chain, Maltose/maltodextrin-binding periplasmic protein,Mucin-16 | | 著者 | Lee, K, Perry, K, Yeku, O.O, Spriggs, D.R. | | 登録日 | 2024-01-22 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structural basis for antibody recognition of the proximal MUC16 ectodomain.
J Ovarian Res, 17, 2024
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6EDI
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4OUJ
 | | Crystal structure of HA33B-Lac | | 分子名称: | Hemagglutinin component HA33, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Lee, K, Lam, K.-H, Perry, K, Rummel, A, Jin, R. | | 登録日 | 2014-02-17 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex.
Biochem.Biophys.Res.Commun., 446, 2014
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4QD2
 | | Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex | | 分子名称: | CALCIUM ION, Cadherin-1, Hemagglutinin component HA17, ... | | 著者 | Lee, K, Zhong, X, Gu, S, Kruel, A, Dorner, M.B, Perry, K, Rummel, A, Dong, M, Jin, R. | | 登録日 | 2014-05-13 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.
Science, 344, 2014
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8UIU
 | | Structure of an FMO from Bacillus niacini | | 分子名称: | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, FLAVIN-ADENINE DINUCLEOTIDE, Flavin monooxygenase | | 著者 | Hicks, K.A, Perry, K. | | 登録日 | 2023-10-10 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Structure of an FMO from Bacillus niacini
To Be Published
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4QNC
 | | Crystal structure of a SemiSWEET in an occluded state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, chemical transport protein | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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4GLI
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4QND
 | | Crystal structure of a SemiSWEET | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ... | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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5FCW
 | | HDAC8 Complexed with a Hydroxamic Acid | | 分子名称: | 4-naphthalen-1-yl-~{N}-oxidanyl-benzamide, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | Cole, K.E, Perry, K. | | 登録日 | 2015-12-15 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | | 主引用文献 | Structure of 'linkerless' hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket.
J.Struct.Biol., 195, 2016
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