2H7F

Structure of variola topoisomerase covalently bound to DNA

Summary for 2H7F

• Entry DOI: 10.2210/pdb2h7f/pdb
• Related: 2H7G
• Descriptor: 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', DNA topoisomerase 1, ... (4 entities in total)
• Functional Keywords: type ib topoisomerase, dna binding, protein-dna complex, isomerase, isomerase-dna complex, isomerase/dna
• Biological source: Variola virus
• Total number of polymer chains: 3
• Total formula weight: 44326.43

Authors

Perry, K.,Hwang, Y.,Bushman, F.D.,Van Duyne, G.D. (deposition date: 2006-06-02, release date: 2006-08-15, Last modification date: 2021-10-20)

• Primary citation: Perry, K.,Hwang, Y.,Bushman, F.D.,Van Duyne, G.D.; Structural basis for specificity in the poxvirus topoisomerase.; Mol.Cell, 23:343-354, 2006; PubMed: 16885024; DOI: 10.1016/j.molcel.2006.06.015

Experimental method

X-RAY DIFFRACTION (2.7 Å)