8VRS

Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody

Summary for 8VRS

• Entry DOI: 10.2210/pdb8vrs/pdb
• Related: 8VRR
• Descriptor: Maltose/maltodextrin-binding periplasmic protein,Mucin-16, 4H11 scFv chain (3 entities in total)
• Functional Keywords: antibody complex epitope cancer therapy immunotherapy mucins, oncoprotein, oncoprotein-immune system complex, oncoprotein/immune system
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 142226.87

Authors

Lee, K.,Perry, K.,Yeku, O.O.,Spriggs, D.R. (deposition date: 2024-01-22, release date: 2024-04-03)

• Primary citation: Lee, K.,Perry, K.,Xu, M.,Veillard, I.,Kumar, R.,Rao, T.D.,Rueda, B.R.,Spriggs, D.R.,Yeku, O.O.; Structural basis for antibody recognition of the proximal MUC16 ectodomain.; J Ovarian Res, 17:41-41, 2024; PubMed: 38374055; DOI: 10.1186/s13048-024-01373-9

Experimental method

X-RAY DIFFRACTION (2.47 Å)