3RZV
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3RZU
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4JKJ
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4DM9
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![BU of 4dm9 by Molmil](/molmil-images/mine/4dm9) | The Crystal Structure of Ubiquitin Carboxy-terminal hydrolase L1 (UCHL1) bound to a tripeptide fluoromethyl ketone Z-VAE(OMe)-FMK | 分子名称: | Tripeptide fluoromethyl ketone inhibitor Z-VAE(OMe)-FMK, Ubiquitin carboxyl-terminal hydrolase isozyme L1 | 著者 | Davies, C.W, Chaney, J, Korbel, G, Ringe, D, Petsko, G.A, Ploegh, H, Das, C. | 登録日 | 2012-02-07 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorg.Med.Chem.Lett., 22, 2012
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3KVF
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3IRT
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8EW6
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![BU of 8ew6 by Molmil](/molmil-images/mine/8ew6) | Anti-human CD8 VHH complex with CD8 alpha | 分子名称: | Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain | 著者 | Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P. | 登録日 | 2022-10-21 | 公開日 | 2022-11-23 | 最終更新日 | 2023-02-01 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging. Eur J Nucl Med Mol Imaging, 50, 2023
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7RP3
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![BU of 7rp3 by Molmil](/molmil-images/mine/7rp3) | Crystal structure of GNE-1952 alkylated KRAS G12C in complex with 2H11 CLAMP | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, ... | 著者 | Oh, A, Tam, C, Wang, W. | 登録日 | 2021-08-03 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7RP2
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![BU of 7rp2 by Molmil](/molmil-images/mine/7rp2) | Crystal structure of Kas G12C in complex with 2H11 CLAMP | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, GTPase KRas, ... | 著者 | Oh, A, Tam, C, Wang, W. | 登録日 | 2021-08-03 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7RP4
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![BU of 7rp4 by Molmil](/molmil-images/mine/7rp4) | Crystal structure of KRAS G12C in complex with GNE-1952 | 分子名称: | 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Oh, A, Tam, C, Wang, W. | 登録日 | 2021-08-03 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7MFR
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![BU of 7mfr by Molmil](/molmil-images/mine/7mfr) | Crystal Structure of a Fab fragment bound to peptide GGM | 分子名称: | Antibody fragment - Heavy Chain of fab, Antibody fragment - Light Chain of fab, GLY-GLY-MET, ... | 著者 | Sudhamsu, J. | 登録日 | 2021-04-10 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.848 Å) | 主引用文献 | Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W. Nat Commun, 12, 2021
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7MDP
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![BU of 7mdp by Molmil](/molmil-images/mine/7mdp) | KRas G12C in complex with G-2897 | 分子名称: | 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 4-(trifluoromethyl)-1,3-benzothiazol-2-amine, ... | 著者 | Oh, A, Frank, Y, Wang, W. | 登録日 | 2021-04-05 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7JWQ
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7JWP
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7U8G
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![BU of 7u8g by Molmil](/molmil-images/mine/7u8g) | Cryo-EM structure of the core human NADPH oxidase NOX2 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ... | 著者 | Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T. | 登録日 | 2022-03-08 | 公開日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the core human NADPH oxidase NOX2. Nat Commun, 13, 2022
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4K1R
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4JXE
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![BU of 4jxe by Molmil](/molmil-images/mine/4jxe) | Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMSH-like protease sst2, ... | 著者 | Shrestha, R.K, Das, C. | 登録日 | 2013-03-28 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.451 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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3KW5
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3IFW
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4MSQ
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![BU of 4msq by Molmil](/molmil-images/mine/4msq) | Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin | 分子名称: | 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ... | 著者 | Shrestha, R.K, Ronau, J.A, Das, C. | 登録日 | 2013-09-18 | 公開日 | 2014-06-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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4MSJ
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![BU of 4msj by Molmil](/molmil-images/mine/4msj) | Crystal structure of S. pombe AMSH-like protease SST2 catalytic domain from P212121 space group | 分子名称: | 1,2-ETHANEDIOL, AMSH-like protease sst2, GLYCINE, ... | 著者 | Shrestha, R.K, Ronau, J.A, Das, C. | 登録日 | 2013-09-18 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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4PQT
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![BU of 4pqt by Molmil](/molmil-images/mine/4pqt) | Insights into the mechanism of deubiquitination by JAMM deubiquitinases from co-crystal structures of enzyme with substrate and product | 分子名称: | 1,2-ETHANEDIOL, AMSH-like protease sst2, Protein UBBP4, ... | 著者 | Shrestha, R.K, Ronau, J.A, Das, C. | 登録日 | 2014-03-04 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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4NQL
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![BU of 4nql by Molmil](/molmil-images/mine/4nql) | The crystal structure of the DUB domain of AMSH orthologue, Sst2 from S. pombe, in complex with lysine 63-linked diubiquitin | 分子名称: | 1,2-ETHANEDIOL, AMSH-like protease sst2, Ubiquitin, ... | 著者 | Ronau, J.A, Shrestha, R.K, Das, C. | 登録日 | 2013-11-25 | 公開日 | 2014-10-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insights into the mechanism of deubiquitination by JAMM deubiquitinases from cocrystal structures of the enzyme with the substrate and product. Biochemistry, 53, 2014
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4MSM
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![BU of 4msm by Molmil](/molmil-images/mine/4msm) | Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 E286A mutant bound to ubiquitin | 分子名称: | 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ... | 著者 | Shrestha, R.K, Ronau, J.A, Das, C. | 登録日 | 2013-09-18 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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4MS7
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![BU of 4ms7 by Molmil](/molmil-images/mine/4ms7) | Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMSH-like protease sst2, ... | 著者 | Shrestha, R.K, Ronau, J.A, Das, C. | 登録日 | 2013-09-18 | 公開日 | 2014-06-18 | 実験手法 | X-RAY DIFFRACTION (1.673 Å) | 主引用文献 | Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53, 2014
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