7JWQ

Fab CJ11 in complex IL-1beta peptide liberated by Caspase cleavage

Summary for 7JWQ

• Entry DOI: 10.2210/pdb7jwq/pdb
• Descriptor: Fab CJ11 Heavy chain, Fab CJ11 Light chain, IL-1beta peptide, ... (4 entities in total)
• Functional Keywords: il-1beta, caspase, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 94337.21

Authors

Payandeh, J.,Ho, H. (deposition date: 2020-08-26, release date: 2021-03-24, Last modification date: 2023-10-18)

• Primary citation: Davies, C.W.,Stowe, I.,Phung, Q.T.,Ho, H.,Bakalarski, C.E.,Gupta, A.,Zhang, Y.,Lill, J.R.,Payandeh, J.,Kayagaki, N.,Koerber, J.T.; Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33723046; DOI: 10.1073/pnas.2018024118

Experimental method

X-RAY DIFFRACTION (2.001 Å)