7JWP
Fab CJ11 in complex IL-18 peptide liberated by Caspase cleavage
Summary for 7JWP
| Entry DOI | 10.2210/pdb7jwp/pdb |
| Descriptor | Fab CJ11 Heavy chain, Fab CJ11 Light chain, IL-18 peptide (3 entities in total) |
| Functional Keywords | il-18, caspase, immune system |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 24 |
| Total formula weight | 376274.77 |
| Authors | Payandeh, J.,Ho, H. (deposition date: 2020-08-26, release date: 2021-03-24, Last modification date: 2023-10-18) |
| Primary citation | Davies, C.W.,Stowe, I.,Phung, Q.T.,Ho, H.,Bakalarski, C.E.,Gupta, A.,Zhang, Y.,Lill, J.R.,Payandeh, J.,Kayagaki, N.,Koerber, J.T. Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33723046DOI: 10.1073/pnas.2018024118 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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