7U8G

Cryo-EM structure of the core human NADPH oxidase NOX2

Summary for 7U8G

• Entry DOI: 10.2210/pdb7u8g/pdb
• EMDB information: 26383
• Descriptor: EGFP, Cytochrome b-245 heavy chain chimera, Cytochrome b-245 light chain, 7G5 - heavy chain, ... (7 entities in total)
• Functional Keywords: heterodimer, complex, nadph oxidase, enzyme, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 170000.59

Authors

Noreng, S.,Ota, N.,Sun, Y.,Masureel, M.,Payandeh, J.,Yi, T.,Koerber, J.T. (deposition date: 2022-03-08, release date: 2022-10-26)

• Primary citation: Noreng, S.,Ota, N.,Sun, Y.,Ho, H.,Johnson, M.,Arthur, C.P.,Schneider, K.,Lehoux, I.,Davies, C.W.,Mortara, K.,Wong, K.,Seshasayee, D.,Masureel, M.,Payandeh, J.,Yi, T.,Koerber, J.T.; Structure of the core human NADPH oxidase NOX2.; Nat Commun, 13:6079-6079, 2022; PubMed: 36241643; DOI: 10.1038/s41467-022-33711-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)