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9C4B
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BU of 9c4b by Molmil
Second BAF53a of the human TIP60 complex
分子名称: Actin-like protein 6A
著者Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
登録日2024-06-03
公開日2024-08-14
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C6N
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BU of 9c6n by Molmil
ARP module of the human TIP60 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
登録日2024-06-07
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C57
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BU of 9c57 by Molmil
Reconstituted P400 Subcomplex of the human TIP60 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
登録日2024-06-05
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C47
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BU of 9c47 by Molmil
TRRAP module of the human TIP60 complex
分子名称: E1A-binding protein p400, Transformation/transcription domain-associated protein
著者Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
登録日2024-06-03
公開日2024-08-14
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C62
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BU of 9c62 by Molmil
P400 subcomplex of the native human TIP60 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
登録日2024-06-07
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (5.28 Å)
主引用文献Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
6NFX
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BU of 6nfx by Molmil
MBTD1 MBT repeats
分子名称: GLYCEROL, MBT domain-containing protein 1,Enhancer of polycomb homolog 1, SODIUM ION, ...
著者Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2018-12-21
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
Cell Rep, 30, 2020
5ERC
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BU of 5erc by Molmil
X-ray crystal structure of BRPF1 PZP domain
分子名称: CALCIUM ION, Peregrin, ZINC ION
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2015-11-13
公開日2015-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res., 44, 2016
6OIE
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BU of 6oie by Molmil
The double PHD finger (DPF) of MORF in complex with histone H3K14cr
分子名称: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2019-04-09
公開日2019-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.075 Å)
主引用文献Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Nat Commun, 10, 2019
6AXJ
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BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
分子名称: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2017-09-06
公開日2017-11-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.379 Å)
主引用文献Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
8GDX
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BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
分子名称: GLYCEROL, Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8GE0
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BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
分子名称: Histone H3.1,Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
分子名称: H3L-like histone, PHD finger protein 1
著者Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
登録日2012-10-01
公開日2012-11-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
5Y81
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BU of 5y81 by Molmil
NuA4 TEEAA sub-complex
分子名称: Actin, Actin-related protein 4, Chromatin modification-related protein EAF1, ...
著者Wang, X, Cai, G.
登録日2017-08-18
公開日2018-04-18
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex
Nat Commun, 9, 2018
3C6W
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BU of 3c6w by Molmil
Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
分子名称: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
著者Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
登録日2008-02-05
公開日2008-06-03
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
5U2J
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BU of 5u2j by Molmil
MORF double PHD finger (DPF) in complex with histone H3K14bu
分子名称: Histone H3K14bu, Histone acetyltransferase KAT6B, ZINC ION
著者Andrews, F.H, Klein, B.J, Kutateladze, T.G.
登録日2016-11-30
公開日2017-04-12
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Recognition of Histone H3K14 Acylation by MORF.
Structure, 25, 2017
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
分子名称: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
著者Zhang, Y, Zandian, M, Kutateladze, T.
登録日2024-02-27
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
3TOA
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BU of 3toa by Molmil
Human MOF crystal structure with active site lysine partially acetylated
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ...
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO6
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BU of 3to6 by Molmil
Crystal structure of yeast Esa1 HAT domain complexed with H4K16CoA bisubstrate inhibitor
分子名称: CARBOXYMETHYL COENZYME *A, Histone H4, Histone acetyltransferase ESA1
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TOB
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BU of 3tob by Molmil
Human MOF E350Q crystal structure with active site lysine partially acetylated
分子名称: CHLORIDE ION, ZINC ION, histone acetyltransferase MYST1
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO7
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BU of 3to7 by Molmil
Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated
分子名称: CACODYLIC ACID, COENZYME A, GLYCEROL, ...
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO9
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BU of 3to9 by Molmil
Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated
分子名称: 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ...
著者Yuan, H, Ding, E.C, Marmorstein, R.
登録日2011-09-04
公開日2011-11-09
最終更新日2012-01-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
6U04
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BU of 6u04 by Molmil
Crystal structure of human BRPF1 PZP bound to histone H3 tail
分子名称: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2019-08-13
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
8W13
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BU of 8w13 by Molmil
Crystal structure of MYST acetyltransferase domain in complex with N-(1-(5-bromo-2-methoxyphenyl)-1H-1,2,3-triazol-4-yl)-2-methoxybenzenesulfonamide
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Histone acetyltransferase KAT8, ...
著者Chen, C, Dou, Y, Wang, M, Xu, C, Buesking, A.
登録日2024-02-15
公開日2024-09-11
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Identification of triazolyl KAT6 inhibitors via a templated fragment approach
Bioorg.Med.Chem.Lett., 2024
7TUQ
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BU of 7tuq by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
分子名称: Bromodomain-containing protein 4, Envelope small membrane protein
著者Vann, K.R, Kutateladze, T.G.
登録日2022-02-03
公開日2022-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
7TV0
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BU of 7tv0 by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with dual-acetylated SARS-CoV-2 E
分子名称: Bromodomain-containing protein 4, Envelope small membrane protein
著者Vann, K.R, Holt, T.A, Kutateladze, T.G.
登録日2022-02-03
公開日2022-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022

 

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