3TO9

Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated

Summary for 3TO9

Entry DOI	10.2210/pdb3to9/pdb
Related	3TO6 3TO7 3TOA 3TOB
Descriptor	Histone acetyltransferase ESA1, COENZYME A, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	myst family, transferase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	1
Total formula weight	34435.95
Authors	Yuan, H.,Ding, E.C.,Marmorstein, R. (deposition date: 2011-09-04, release date: 2011-11-09, Last modification date: 2012-01-18)
Primary citation	Yuan, H.,Rossetto, D.,Mellert, H.,Dang, W.,Srinivasan, M.,Johnson, J.,Hodawadekar, S.,Ding, E.C.,Speicher, K.,Abshiru, N.,Perry, R.,Wu, J.,Yang, C.,Zheng, Y.G.,Speicher, D.W.,Thibault, P.,Verreault, A.,Johnson, F.B.,Berger, S.L.,Sternglanz, R.,McMahon, S.B.,Cote, J.,Marmorstein, R. MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31:58-70, 2011 Cited by PubMed: 22020126 DOI: 10.1038/emboj.2011.382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation