6AXJ

Crystal structure of the Yaf9 YEATS domain bound to H3K27ac

Summary for 6AXJ

• Entry DOI: 10.2210/pdb6axj/pdb
• Descriptor: Protein AF-9 homolog, ALY-SER-ALA-PRO-ALA, SULFATE ION, ... (5 entities in total)
• Functional Keywords: epigenetic, gene regulation, transcription
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Cytoplasm: P53930
• Total number of polymer chains: 8
• Total formula weight: 83213.06

Authors

Klein, B.J.,Kutateladze, T.G. (deposition date: 2017-09-06, release date: 2017-11-22, Last modification date: 2018-01-24)

• Primary citation: Klein, B.J.,Ahmad, S.,Vann, K.R.,Andrews, F.H.,Mayo, Z.A.,Bourriquen, G.,Bridgers, J.B.,Zhang, J.,Strahl, B.D.,Cote, J.,Kutateladze, T.G.; Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.; Nucleic Acids Res., 46:421-430, 2018; PubMed: 29145630; DOI: 10.1093/nar/gkx1151

Experimental method

X-RAY DIFFRACTION (2.379 Å)