6AXJ

Crystal structure of the Yaf9 YEATS domain bound to H3K27ac

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006355	biological_process	regulation of DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue SO4 A 201

Chain	Residue
A	HIS67
A	PHE92
A	ASP93
A	ARG114
A	HOH320
A	HOH326
A	HOH335
A	HOH358
B	LYS65

---

site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 A 202

Chain	Residue
A	LYS65
A	HOH318
A	HOH340
A	HOH395
B	HIS67
B	PHE92
B	ASP93
B	ARG114
B	HOH309

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 203

Chain	Residue
A	TYR149
A	ASP151
A	HOH302
A	HOH328
A	HOH359

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 204

Chain	Residue
A	THR23
A	ARG48
A	GLU83
B	VAL30

---

site_id	AC5
Number of Residues	9
Details	binding site for residue SO4 C 201

Chain	Residue
C	LYS65
C	HOH314
C	HOH322
C	HOH343
D	HIS67
D	PHE92
D	ASP93
D	ARG114
D	HOH311

---

site_id	AC6
Number of Residues	9
Details	binding site for residue SO4 C 202

Chain	Residue
C	HIS67
C	PHE92
C	ASP93
C	ARG114
C	HOH315
C	HOH328
C	HOH342
C	HOH351
D	LYS65

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL C 203

Chain	Residue
C	THR23
C	PHE46
C	ARG48
C	GLU83
C	HOH323
C	HOH326

---

site_id	AC8
Number of Residues	4
Details	binding site for residue GOL B 201

Chain	Residue
B	THR23
B	ARG48
B	GLU83
B	HOH365

---

site_id	AC9
Number of Residues	3
Details	binding site for residue GOL B 202

Chain	Residue
B	VAL148
B	TYR149
B	HOH317

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL B 203

Chain	Residue
B	GLY6
B	ALA104
B	ASN105
B	GLU106
B	GLU157
B	ASN159

---

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL B 204

Chain	Residue
B	GLU38
B	TRP89
B	HOH344

---

site_id	AD3
Number of Residues	7
Details	binding site for residue GOL D 201

Chain	Residue
D	HIS39
D	TYR70
D	PRO71
D	ARG75
D	GLU86
D	THR87
D	HOH307

---

site_id	AD4
Number of Residues	4
Details	binding site for residue GOL D 202

Chain	Residue
D	TYR149
D	ASP151
D	HOH303
D	HOH309

---

site_id	AD5
Number of Residues	3
Details	binding site for residue GOL D 203

Chain	Residue
A	ASN72
D	ASN72
D	HOH325

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708

Chain	Residue	Details
G	LYS23
E	LYS23
H	LYS23
F	LYS23

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Citrulline => ECO:0000269|PubMed:16567635

Chain	Residue	Details
G	ARG26
E	ARG26
H	ARG26
F	ARG26

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708

Chain	Residue	Details
G	ALY27
E	ALY27
H	ALY27
F	ALY27

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588

Chain	Residue	Details
G	SER28
E	SER28
H	SER28
F	SER28

---