7TUQ
Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
Summary for 7TUQ
Entry DOI | 10.2210/pdb7tuq/pdb |
Descriptor | Bromodomain-containing protein 4, Envelope small membrane protein (3 entities in total) |
Functional Keywords | brd4, bromodomain, sars-cov-2, covid, envelope protein, e protein, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 33872.91 |
Authors | Vann, K.R.,Kutateladze, T.G. (deposition date: 2022-02-03, release date: 2022-07-06, Last modification date: 2023-11-15) |
Primary citation | Vann, K.R.,Acharya, A.,Jang, S.M.,Lachance, C.,Zandian, M.,Holt, T.A.,Smith, A.L.,Pandey, K.,Durden, D.L.,El-Gamal, D.,Cote, J.,Byrareddy, S.N.,Kutateladze, T.G. Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection. Structure, 30:1224-, 2022 Cited by PubMed: 35716662DOI: 10.1016/j.str.2022.05.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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