7UKM
 
 | |
7M8K
 | | Cryo-EM structure of Brazil (P.1) SARS-CoV-2 spike glycoprotein variant in the prefusion state (1 RBD up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Casner, R.G, Cerutti, G, Shapiro, L, Ho, D.D. | | 登録日 | 2021-03-29 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization.
Cell Host Microbe, 29, 2021
|
|
7N5H
 | | Cryo-EM structure of broadly neutralizing antibody 2-36 in complex with prefusion SARS-CoV-2 spike glycoprotein | | 分子名称: | 2-36 Fab heavy chain, 2-36 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Casner, R.G, Cerutti, G, Shapiro, L. | | 登録日 | 2021-06-05 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses.
Emerg Microbes Infect, 11, 2022
|
|
7UKL
 | |
8DEQ
 | | Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ... | | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-06-21 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8DER
 | | Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ... | | 著者 | Casner, R.G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-06-21 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
7MXP
 | | Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Reddem, E.R, Casner, R.G, Shapiro, L. | | 登録日 | 2021-05-19 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2.
Aiche J, 67, 2021
|
|
7SD5
 | | Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain | | 分子名称: | 10-40 Heavy chain, 10-40 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Reddem, E.R, Casner, R.G, Shapiro, L. | | 登録日 | 2021-09-29 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.
Sci Transl Med, 14, 2022
|
|
6PW5
 | | Cryo-EM Structure of Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas reinhardtii in Nanodiscs | | 分子名称: | (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, TRP-like ion channel, ... | | 著者 | McGoldrick, L.L, Singh, A.K, Sobolevsky, A.I. | | 登録日 | 2019-07-22 | | 公開日 | 2019-09-25 | | 最終更新日 | 2019-12-04 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii.
Nat Commun, 10, 2019
|
|
6PW4
 | | Cryo-EM Structure of Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas reinhardtii in Detergent | | 分子名称: | (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | 著者 | McGoldrick, L.L, Singh, A.K, Sobolevsky, A.I. | | 登録日 | 2019-07-22 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii.
Nat Commun, 10, 2019
|
|
7SI2
 | |
7TTM
 | |
7TTX
 | |
7TTY
 | |
7TZ0
 | |
7TYZ
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ... | | 著者 | Kwon, Y.D, Gorman, J, Kwong, P.D. | | 登録日 | 2022-02-15 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
|
|
8DW2
 | | Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022 | | 分子名称: | Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ... | | 著者 | Kwon, Y.D, Gorman, J, Kwong, P.D. | | 登録日 | 2022-07-30 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | | 主引用文献 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
|
|
8DW3
 | | Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022 | | 分子名称: | Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ... | | 著者 | Kwon, Y.D, Gorman, J, Kwong, P.D. | | 登録日 | 2022-07-30 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | | 主引用文献 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
|
|
8DUL
 | | Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8DUN
 | | Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (5.84 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8EEU
 | | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05 | | 分子名称: | Coat protein, Fab SKT05 heavy chain, Fab SKT05 light chain | | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8EEV
 | | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20 | | 分子名称: | Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain | | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8DWO
 | | Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab | | 分子名称: | Envelope glycoprotein E1, Envelope glycoprotein E2, SKE26 Fab Heavy Chain, ... | | 著者 | Pletnev, S, Verardi, R, Roedeger, M, Kwong, P. | | 登録日 | 2022-08-01 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8DEC
 | | Cryo-EM Structure of Western Equine Encephalitis Virus | | 分子名称: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2 | | 著者 | Pletnev, S, Verardi, R, Roedeger, M, Kwong, P. | | 登録日 | 2022-06-20 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
8DED
 | | Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW19 fab | | 分子名称: | SKW19 Fab heavy chain, SKW19 Fab light chain, Spike glycoprotein E1, ... | | 著者 | Pletnev, S, Tsybovsky, Y, Verardi, R, Roedeger, M, Kwong, P. | | 登録日 | 2022-06-20 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
|
|
