8DWO

Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab

Summary for 8DWO

Entry DOI	10.2210/pdb8dwo/pdb
EMDB information	27757
Descriptor	Envelope glycoprotein E1, Envelope glycoprotein E2, SKE26 Fab Heavy Chain, ... (4 entities in total)
Functional Keywords	eastern equine encephalitis virus, virus like particle, virus-fab complex
Biological source	Eastern equine encephalitis virus More
Total number of polymer chains	12
Total formula weight	431726.48
Authors	Pletnev, S.,Verardi, R.,Roedeger, M.,Kwong, P. (deposition date: 2022-08-01, release date: 2023-07-19, Last modification date: 2023-09-27)
Primary citation	Sutton, M.S.,Pletnev, S.,Callahan, V.,Ko, S.,Tsybovsky, Y.,Bylund, T.,Casner, R.G.,Cerutti, G.,Gardner, C.L.,Guirguis, V.,Verardi, R.,Zhang, B.,Ambrozak, D.,Beddall, M.,Lei, H.,Yang, E.S.,Liu, T.,Henry, A.R.,Rawi, R.,Schon, A.,Schramm, C.A.,Shen, C.H.,Shi, W.,Stephens, T.,Yang, Y.,Florez, M.B.,Ledgerwood, J.E.,Burke, C.W.,Shapiro, L.,Fox, J.M.,Kwong, P.D.,Roederer, M. Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186:2672-2689.e25, 2023 Cited by PubMed: 37295404 DOI: 10.1016/j.cell.2023.05.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation