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7N5H

Cryo-EM structure of broadly neutralizing antibody 2-36 in complex with prefusion SARS-CoV-2 spike glycoprotein

Summary for 7N5H
Entry DOI10.2210/pdb7n5h/pdb
EMDB information24190
DescriptorSpike glycoprotein, 2-36 Fab heavy chain, 2-36 Fab light chain, ... (5 entities in total)
Functional Keywordssars-cov-2, viral spike, trimer, glycoprotein, neutralizing antibody fab, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains9
Total formula weight513329.87
Authors
Casner, R.G.,Cerutti, G.,Shapiro, L. (deposition date: 2021-06-05, release date: 2021-11-03, Last modification date: 2022-11-16)
Primary citationWang, P.,Casner, R.G.,Nair, M.S.,Yu, J.,Guo, Y.,Wang, M.,Chan, J.F.,Cerutti, G.,Iketani, S.,Liu, L.,Sheng, Z.,Chen, Z.,Yuen, K.Y.,Kwong, P.D.,Huang, Y.,Shapiro, L.,Ho, D.D.
A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses.
Emerg Microbes Infect, 11:147-157, 2022
Cited by
PubMed: 34836485
DOI: 10.1080/22221751.2021.2011623
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.24 Å)
Structure validation

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