7SI2
Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD)
Summary for 7SI2
Entry DOI | 10.2210/pdb7si2/pdb |
Descriptor | 10-28 Light Chain, 10-28 Heavy Chain, Spike protein S1, ... (4 entities in total) |
Functional Keywords | covid-19, sars-cov-2, viral protein, spike glycoprotein, receptor binding protein, rbd, neutralizing antibody, 10-28, fab, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 223704.94 |
Authors | Reddem, E.R.,Shapiro, L. (deposition date: 2021-10-12, release date: 2022-04-27, Last modification date: 2023-10-18) |
Primary citation | Liu, L.,Iketani, S.,Guo, Y.,Reddem, E.R.,Casner, R.G.,Nair, M.S.,Yu, J.,Chan, J.F.,Wang, M.,Cerutti, G.,Li, Z.,Morano, N.C.,Castagna, C.D.,Corredor, L.,Chu, H.,Yuan, S.,Poon, V.K.,Chan, C.C.,Chen, Z.,Luo, Y.,Cunningham, M.,Chavez, A.,Yin, M.T.,Perlin, D.S.,Tsuji, M.,Yuen, K.Y.,Kwong, P.D.,Sheng, Z.,Huang, Y.,Shapiro, L.,Ho, D.D. An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14:eabn6859-eabn6859, 2022 Cited by PubMed: 35438546DOI: 10.1126/scitranslmed.abn6859 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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