7SI2

Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	D, F, L	10-28 Light Chain	polymer	216	23384.9	3		Homo sapiens (Human)
2	E, G, H	10-28 Heavy Chain	polymer	226	24186.2	3		Homo sapiens (Human)
3	A, B, C	Spike protein S1	polymer	236	26572.9	3	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
4	I, J, K	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)

Sequence modifications

A, B, C: 319 - 537 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 538	-	expression tag
Ser 539	-	expression tag
Leu 540	-	expression tag
Glu 541	-	expression tag
Val 542	-	expression tag
Leu 543	-	expression tag
Phe 544	-	expression tag
Gln 545	-	expression tag
Gly 546	-	expression tag
Pro 547	-	expression tag
Gly 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	222431.7
Branched	Number of molecules	3
	Total formula weight	1273.2
All*	Total formula weight	223704.9

*Water molecules are not included.