8DER

Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein

Summary for 8DER

Entry DOI	10.2210/pdb8der/pdb
EMDB information	27396
Descriptor	SKV16 Fab Heavy Chain, SKV16 Fab Light Chain, Spike glycoprotein E1, ... (7 entities in total)
Functional Keywords	antibody alphavirus veev spike trimer glycoprotein, viral protein
Biological source	Macaca More
Total number of polymer chains	12
Total formula weight	322856.44
Authors	Casner, R.G.,Verardi, R.,Roederer, M.,Shapiro, L. (deposition date: 2022-06-21, release date: 2023-06-28)
Primary citation	Sutton, M.S.,Pletnev, S.,Callahan, V.,Ko, S.,Tsybovsky, Y.,Bylund, T.,Casner, R.G.,Cerutti, G.,Gardner, C.L.,Guirguis, V.,Verardi, R.,Zhang, B.,Ambrozak, D.,Beddall, M.,Lei, H.,Yang, E.S.,Liu, T.,Henry, A.R.,Rawi, R.,Schon, A.,Schramm, C.A.,Shen, C.H.,Shi, W.,Stephens, T.,Yang, Y.,Florez, M.B.,Ledgerwood, J.E.,Burke, C.W.,Shapiro, L.,Fox, J.M.,Kwong, P.D.,Roederer, M. Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186:2672-2689.e25, 2023 Cited by PubMed: 37295404 DOI: 10.1016/j.cell.2023.05.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation