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1D8D
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BU of 1d8d by Molmil
CO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION
分子名称: ACETATE ION, K-RAS4B PEPTIDE SUBSTRATE, ZINC ION, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日1999-10-22
公開日2000-02-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Structure Fold.Des., 8, 2000
1D8E
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BU of 1d8e by Molmil
Zinc-depleted FTase complexed with K-RAS4B peptide substrate and FPP analog.
分子名称: ACETATE ION, FARNESYLTRANSFERASE (ALPHA SUBUNIT), FARNESYLTRANSFERASE (BETA SUBUNIT), ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日1999-10-22
公開日2000-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Structure Fold.Des., 8, 2000
1KZP
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BU of 1kzp by Molmil
PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT
分子名称: ACETIC ACID, FARNESYL, Farnesylated K-Ras4B peptide product, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日2002-02-07
公開日2002-10-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reaction path of protein farnesyltransferase at atomic resolution
Nature, 419, 2002
1KZO
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BU of 1kzo by Molmil
PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY
分子名称: ACETIC ACID, FARNESYL, FARNESYL DIPHOSPHATE, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日2002-02-07
公開日2002-10-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Reaction Path of Protein Farnesyltransferase at Atomic Resolution
Nature, 419, 2002
1FT2
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BU of 1ft2 by Molmil
CO-CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYL DIPHOSPHATE SUBSTRATE
分子名称: FARNESYL DIPHOSPHATE, PROTEIN FARNESYLTRANSFERASE, ZINC ION
著者Beese, L.S, Casey, P.J, Long, S.B.
登録日1998-06-02
公開日1998-11-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
Biochemistry, 37, 1998
1JCS
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BU of 1jcs by Molmil
CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE
分子名称: ACETIC ACID, PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日2001-06-11
公開日2001-11-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JCR
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BU of 1jcr by Molmil
CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE
分子名称: ACETIC ACID, FARNESYL DIPHOSPHATE, PROTEIN FARNESYLTRANSFERASE, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日2001-06-11
公開日2001-11-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JCQ
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CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750
分子名称: 2(S)-{2(S)-[2(R)-AMINO-3-MERCAPTO]PROPYLAMINO-3(S)-METHYL}PENTYLOXY-3-PHENYLPROPIONYLMETHIONINE SULFONE, ACETIC ACID, FARNESYL DIPHOSPHATE, ...
著者Long, S.B, Casey, P.J, Beese, L.S.
登録日2001-06-11
公開日2001-11-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1N4R
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BU of 1n4r by Molmil
Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4P
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Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate
分子名称: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4Q
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Protein Geranylgeranyltransferase type-I Complexed with a GGPP Analog and a KKKSKTKCVIL Peptide
分子名称: 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4S
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Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product
分子名称: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1TNZ
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Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a RRCVLL Peptide Derived from Cdc42 splice isoform-2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TN6
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Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution
分子名称: ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity
J.Mol.Biol., 343, 2004
1TN7
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Protein Farnesyltransferase Complexed with a TC21 Peptide Substrate and a FPP Analog at 2.3A Resolution
分子名称: ACETIC ACID, Fusion protein, Protein farnesyltransferase alpha subunit, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNU
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Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a GCINCCKVL Peptide Derived from RhoB
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNB
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Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNO
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Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TN8
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Protein Farnesyltransferase Complexed with a H-Ras Peptide Substrate and a FPP Analog at 2.25A Resolution
分子名称: ACETIC ACID, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
著者Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNY
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Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a FREKKFFCAIL Peptide Derived from the Heterotrimeric G Protein Gamma-2 Subunit
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
著者S Reid, T, Terry, K.L, Casey, P.J, Beese, L.S.
登録日2004-06-11
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1FT1
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CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE AT 2.25 ANGSTROMS RESOLUTION
分子名称: PROTEIN FARNESYLTRANSFERASE, ZINC ION
著者Beese, L.S, Park, H.-W.
登録日1997-03-17
公開日1998-03-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution.
Science, 275, 1997
2H6G
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W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 1.85A Resolution
分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6F
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Protein Farnesyltransferase Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.5A Resolution
分子名称: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6I
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W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 3.0A
分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H6H
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Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.8A
分子名称: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ...
著者Terry, K.L, Beese, L.S.
登録日2006-05-31
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006

 

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