1KZO

PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY

Summary for 1KZO

Entry DOI	10.2210/pdb1kzo/pdb
Related	1D8D 1FT1 1FT2 1JCQ 1kzp 1kzr
Descriptor	Protein Farnesyltransferase alpha subunit, Protein Farnesyltransferase beta subunit, Farnesylated K-Ras4B peptide product, ... (8 entities in total)
Functional Keywords	ftase, pft, pftase, ft, fpt, farnesyltransferase, farnesyl transferase, farnesyl protein transferase, caax, ras, cancer, product, substrate, transferase-transferase substrate complex, transferase/transferase substrate
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	3
Total formula weight	94833.30
Authors	Long, S.B.,Casey, P.J.,Beese, L.S. (deposition date: 2002-02-07, release date: 2002-10-16, Last modification date: 2023-08-16)
Primary citation	Long, S.B.,Casey, P.J.,Beese, L.S. The Reaction Path of Protein Farnesyltransferase at Atomic Resolution Nature, 419:645-650, 2002 Cited by PubMed: 12374986 DOI: 10.1038/nature00986 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation