1FT2

CO-CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYL DIPHOSPHATE SUBSTRATE

Summary for 1FT2
DescriptorPROTEIN FARNESYLTRANSFERASE, ZINC ION, FARNESYL DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsprotein farnesyltransferase, farnesyl diphosphate, cancer therapeutics, prenyltransferase, isoprenoid, transferase
Biological sourceRattus norvegicus (Norway rat)
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Total number of polymer chains2
Total formula weight83305.74
Authors
Beese, L.S.,Casey, P.J.,Long, S.B. (deposition date: 1998-06-02, release date: 1998-11-04, Last modification date: 2011-07-13)
Primary citationBeese, L.S.,Casey, P.J.,Long, S.B.
Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
Biochemistry, 37:9612-9618, 1998
PubMed: 9657673
DOI: 110.1021/bi980708e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation
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PDB entries from 2021-06-16