1TNY

Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a FREKKFFCAIL Peptide Derived from the Heterotrimeric G Protein Gamma-2 Subunit

Summary for 1TNY

Entry DOI	10.2210/pdb1tny/pdb
Related	1D8D 1N4P 1N4Q 1QBQ 1TN6 1TN7 1TN8 1TNB 1TNO 1TNU 1TNZ
Descriptor	geranylgeranyltransferase type I alpha subunit, Geranylgeranyl transferase type I beta subunit, guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, ... (8 entities in total)
Functional Keywords	ggtase-i, geranylgeranyltransferase type-i, geranylgeranyl transferase, prenyltransferase, caax, heterotrimeric g protein, lipid modification, prenylation, substrate selectivity, transferase
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	18
Total formula weight	531335.46
Authors	S Reid, T.,Terry, K.L.,Casey, P.J.,Beese, L.S. (deposition date: 2004-06-11, release date: 2004-11-02, Last modification date: 2023-08-23)
Primary citation	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343:417-433, 2004 Cited by PubMed: 15451670 DOI: 10.1016/j.jmb.2004.08.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation