1TNO
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B
Summary for 1TNO
Entry DOI | 10.2210/pdb1tno/pdb |
Related | 1D8D 1N4P 1N4Q 1QBQ 1TN6 1TN7 1TN8 1TNB 1TNU 1TNY 1TNZ |
Descriptor | geranylgeranyltransferase type I alpha subunit, Geranylgeranyl transferase type I beta subunit, c-K-ras2 protein isoform b, ... (8 entities in total) |
Functional Keywords | ggtase-i, geranylgeranyltransferase type-i, geranylgeranyl transferase, prenyltransferase, caax, ras, k-ras, lipid modification, prenylation, substrate selectivity, transferase |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 18 |
Total formula weight | 530823.69 |
Authors | Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. (deposition date: 2004-06-11, release date: 2004-11-02, Last modification date: 2023-08-23) |
Primary citation | Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343:417-433, 2004 Cited by PubMed: 15451670DOI: 10.1016/j.jmb.2004.08.056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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