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1TNO

Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I...
(A, C, E, G, I...)
geranylgeranyltransferase type I alpha subunitpolymer37744098.16UniProt (Q04631)
Pfam (PF01239)
Rattus norvegicus (Norway rat)Type I protein geranyl-geranyltransferase alpha subunit, GGTase-I-alpha
2B, D, F, H, J...
(B, D, F, H, J...)
Geranylgeranyl transferase type I beta subunitpolymer37742466.26UniProt (P53610)
Pfam (PF00432)
Rattus norvegicus (Norway rat)Type I protein geranyl-geranyltransferase beta subunit, GGTase-I-beta
3M, N, O, P, Q...
(M, N, O, P, Q...)
c-K-ras2 protein isoform bpolymer111298.76
4CA, FA, HA, S, V...
(H, J, L, B, D...)
ZINC IONnon-polymer65.46Chemie (ZN)
5AA, T
(F, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
6BA, EA, GA, JA, U...
(F, H, J, L, B...)
2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATEnon-polymer453.46Chemie (MGM)
7DA, IA, W, Z
(H, L, D, F)
CHLORIDE IONnon-polymer35.54Chemie (CL)
8AB, KA, LA, MA, NA...
(R, A, B, C, D...)
waterwater18.0678Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight527178.3
Non-Polymers*Number of molecules18
Total formula weight3645.4
All*Total formula weight530823.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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