2H6G
W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 1.85A Resolution
Summary for 2H6G
| Entry DOI | 10.2210/pdb2h6g/pdb |
| Related | 1FPP 1JCQ 1KZP 1N4R 1TN8 2H6F 2H6H 2H6I |
| Related PRD ID | PRD_900003 |
| Descriptor | Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, farnesylated peptide, ... (7 entities in total) |
| Functional Keywords | ftase, farnesyltransferase, farnesyl transferase, prenyltransferase, caax, ras, lipid modification, prenylation, substrate selectivity, transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 95362.48 |
| Authors | Terry, K.L.,Beese, L.S. (deposition date: 2006-05-31, release date: 2006-08-29, Last modification date: 2023-08-30) |
| Primary citation | Terry, K.L.,Casey, P.J.,Beese, L.S. Conversion of protein farnesyltransferase to a geranylgeranyltransferase. Biochemistry, 45:9746-9755, 2006 Cited by PubMed: 16893176DOI: 10.1021/bi060295e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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