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1YNM
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BU of 1ynm by Molmil
Crystal structure of restriction endonuclease HinP1I
分子名称: R.HinP1I restriction endonuclease
著者Yang, Z, Horton, J.R, Maunus, R, Wilson, G.G, Roberts, R.J, Cheng, X.
登録日2005-01-24
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI
Nucleic Acids Res., 33, 2005
4QW2
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BU of 4qw2 by Molmil
FMRP N-terminal domain (R138Q)
分子名称: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1, LEAD (II) ION
著者Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
登録日2014-07-16
公開日2014-12-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
4QVZ
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FMRP N-terminal domain
分子名称: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1
著者Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
登録日2014-07-16
公開日2014-12-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.195 Å)
主引用文献Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
3SVM
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BU of 3svm by Molmil
Human MPP8 - human DNMT3AK47me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-12
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
3SWC
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BU of 3swc by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4RNW
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BU of 4rnw by Molmil
Truncated version of the G303 Circular Permutation of Old Yellow Enzyme
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ...
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
6UKG
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BU of 6ukg by Molmil
HhaI endonuclease in Complex With DNA in space group P21 (pH 4.2)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKF
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HhaI endonuclease in Complex with DNA at 1 Angstrom Resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
3SW9
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BU of 3sw9 by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4RNX
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BU of 4rnx by Molmil
K154 Circular Permutation of Old Yellow Enzyme
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
6UKI
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BU of 6uki by Molmil
HhaI endonuclease in Complex with DNA in space group P212121 (pH 6.0)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
4RNU
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BU of 4rnu by Molmil
G303 Circular Permutation of Old Yellow Enzyme
分子名称: FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, PHOSPHATE ION
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.677 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
4RNV
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BU of 4rnv by Molmil
G303 Circular Permutation of Old Yellow Enzyme with the Inhibitor p-Hydroxybenzaldehyde
分子名称: FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, P-HYDROXYBENZALDEHYDE
著者Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
登録日2014-10-26
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.473 Å)
主引用文献STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
6V62
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BU of 6v62 by Molmil
SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine
分子名称: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2019-12-04
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
6UKH
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BU of 6ukh by Molmil
HhaI endonuclease in Complex with DNA in space group P41212 (pH 6.0)
分子名称: CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*G)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKE
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BU of 6uke by Molmil
HhaI endonuclease in Complex with Iodine-Labelled DNA
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6V63
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BU of 6v63 by Molmil
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2019-12-04
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
8MHT
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BU of 8mht by Molmil
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
分子名称: 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
著者O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
登録日1998-08-06
公開日1998-11-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
7LJC
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BU of 7ljc by Molmil
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
分子名称: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
7LJD
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BU of 7ljd by Molmil
Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
分子名称: 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
3U78
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E67-2 selectively inhibits KIAA1718, a human histone H3 lysine 9 Jumonji demethylase
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, ...
著者Upadhyay, A.K, Cheng, X.
登録日2011-10-13
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases.
J.Mol.Biol., 416, 2012
4JGC
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BU of 4jgc by Molmil
Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC)
分子名称: 4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid, G/T mismatch-specific thymine DNA glycosylase, oligonucleotide, ...
著者Hashimoto, H, Zhang, X, Cheng, X.
登録日2013-02-28
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH.
Dna Repair, 12, 2013
4LT5
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Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
分子名称: 1,2-ETHANEDIOL, DNA, MANGANESE (II) ION, ...
著者Hashimoto, H, Pais, J.E, Zhang, X, Saleh, L, Fu, Z.Q, Dai, N, Correa, I.R, Roberts, R.J, Zheng, Y, Cheng, X.
登録日2013-07-23
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.893 Å)
主引用文献Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Nature, 506, 2014
4M9E
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Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA
分子名称: ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ...
著者Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X.
登録日2013-08-14
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structural basis for Klf4 recognition of methylated DNA.
Nucleic Acids Res., 42, 2014
4M9V
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Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Liu, Y, Olanrewaju, Y.O, Zhang, X, Cheng, X.
登録日2013-08-15
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.969 Å)
主引用文献DNA recognition of 5-carboxylcytosine by a zfp57 mutant at an atomic resolution of 0.97 angstrom.
Biochemistry, 52, 2013

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