10MH

TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET

Summary for 10MH

DescriptorDNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*5NCP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), ... (5 entities in total)
Functional Keywordstransferase, methyltransferase, restriction system, complex (methyltransferase- dna), transferase-dna complex, transferase/dna
Biological sourceHaemophilus haemolyticus
Total number of polymer chains3
Total molecular weight44768.42
Authors
Sheikhnejad, G.,Brank, A.,Christman, J.K.,Goddard, A.,Alvarez, E.,Ford Junior, H.,Marquez, V.E.,Marasco, C.J.,Sufrin, J.R.,O'Gara, M.,Cheng, X. (deposition date: 1998-08-10, release date: 1999-02-09, Last modification date: 2011-07-13)
Primary citation
Sheikhnejad, G.,Brank, A.,Christman, J.K.,Goddard, A.,Alvarez, E.,Ford Jr., H.,Marquez, V.E.,Marasco, C.J.,Sufrin, J.R.,O'gara, M.,Cheng, X.
Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
J.Mol.Biol., 285:2021-2034, 1999
PubMed: 9925782 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1998.2426
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.55 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers40.6%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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