GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide

Summary for 3SWC

Related3SW9 3SVM
DescriptorHistone-lysine N-methyltransferase EHMT1, DNA (cytosine-5)-methyltransferase 3A, ZINC ION, ... (5 entities in total)
Functional Keywordsepigenetics, non-histone lysine methylation, set domain, protein lysine methyltransferase, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9H9B1 O88508
Total number of polymer chains4
Total molecular weight69525.55
Chang, Y.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2011-07-13, release date: 2011-11-30)
Primary citation
Chang, Y.,Sun, L.,Kokura, K.,Horton, J.R.,Fukuda, M.,Espejo, A.,Izumi, V.,Koomen, J.M.,Bedford, M.T.,Zhang, X.,Shinkai, Y.,Fang, J.,Cheng, X.
MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2:533-533, 2011
PubMed: 22086334 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms1549
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.218111.7%4.1%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution