3SWC
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
Summary for 3SWC
Entry DOI | 10.2210/pdb3swc/pdb |
Related | 3SVM 3SW9 |
Descriptor | Histone-lysine N-methyltransferase EHMT1, DNA (cytosine-5)-methyltransferase 3A, ZINC ION, ... (5 entities in total) |
Functional Keywords | epigenetics, non-histone lysine methylation, set domain, protein lysine methyltransferase, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9H9B1 O88508 |
Total number of polymer chains | 4 |
Total formula weight | 69525.55 |
Authors | Chang, Y.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2011-07-13, release date: 2011-11-30, Last modification date: 2023-09-13) |
Primary citation | Chang, Y.,Sun, L.,Kokura, K.,Horton, J.R.,Fukuda, M.,Espejo, A.,Izumi, V.,Koomen, J.M.,Bedford, M.T.,Zhang, X.,Shinkai, Y.,Fang, J.,Cheng, X. MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2:533-533, 2011 Cited by PubMed: 22086334DOI: 10.1038/ncomms1549 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.332 Å) |
Structure validation
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