8TCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tcc by Molmil](/molmil-images/mine/8tcc) | |
7YLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ylm by Molmil](/molmil-images/mine/7ylm) | Cryo-EM structure of 8-subunit Smc5/6 hinge region | 分子名称: | MMS21 isoform 1, SMC6 isoform 1, Structural maintenance of chromosomes protein 5 | 著者 | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | 登録日 | 2022-07-26 | 公開日 | 2024-01-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (6.17 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
|
|
7YQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yqh by Molmil](/molmil-images/mine/7yqh) | Cryo-EM structure of 8-subunit Smc5/6 | 分子名称: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, ... | 著者 | Qian, L, Jun, Z, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W. | 登録日 | 2022-08-07 | 公開日 | 2024-01-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
|
|
6J1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j1u by Molmil](/molmil-images/mine/6j1u) | influenza virus nucleoprotein with a specific inhibitor | 分子名称: | Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide | 著者 | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | 登録日 | 2018-12-29 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle. J.Virol., 95, 2021
|
|
8FQ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fq7 by Molmil](/molmil-images/mine/8fq7) | Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils | 分子名称: | GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils | 著者 | Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S. | 登録日 | 2023-01-05 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6BG9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bg9 by Molmil](/molmil-images/mine/6bg9) | |
3O3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o3k by Molmil](/molmil-images/mine/3o3k) | Crystal structure of AF1382 from Archaeoglobus fulgidus | 分子名称: | Uncharacterized protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-07-24 | 公開日 | 2010-08-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
|
|
4LCZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lcz by Molmil](/molmil-images/mine/4lcz) | Crystal structure of a multilayer-packed major light-harvesting complex | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | 著者 | Wan, T, Li, M, Chang, W.R. | 登録日 | 2013-06-24 | 公開日 | 2014-05-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a multilayer packed major light-harvesting complex: implications for grana stacking in higher plants. Mol Plant, 7, 2014
|
|
8GVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gvk by Molmil](/molmil-images/mine/8gvk) | |
6N6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n6b by Molmil](/molmil-images/mine/6n6b) | |
5YRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yrn by Molmil](/molmil-images/mine/5yrn) | Structure of RIP2 CARD domain | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Wu, B, Gong, Q. | 登録日 | 2017-11-09 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of RIP2 activation and signaling. Nat Commun, 9, 2018
|
|
3OV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ov8 by Molmil](/molmil-images/mine/3ov8) | Crystal structure of AF1382 from Archaeoglobus fulgidus, High resolution | 分子名称: | ACETATE ION, CHLORIDE ION, Protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Hao, X, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-09-16 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8501 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
|
|
8CWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cww by Molmil](/molmil-images/mine/8cww) | Structure of S. cerevisiae Hop1 CBR bound to a nucleosome | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | 登録日 | 2022-05-19 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation. Embo J., 43, 2024
|
|
8GRA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gra by Molmil](/molmil-images/mine/8gra) | |
8CZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cze by Molmil](/molmil-images/mine/8cze) | Structure of a Xenopus Nucleosome with Widom 601 DNA | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | 登録日 | 2022-05-24 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation. Embo J., 43, 2024
|
|
3P08
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3p08 by Molmil](/molmil-images/mine/3p08) | |
8GVL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gvl by Molmil](/molmil-images/mine/8gvl) | PTPN21 FERM | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21 | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | 登録日 | 2022-09-15 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity. Sci Adv, 10, 2024
|
|
8GWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gwh by Molmil](/molmil-images/mine/8gwh) | |
6N4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n4f by Molmil](/molmil-images/mine/6n4f) | |
8GVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gvv by Molmil](/molmil-images/mine/8gvv) | PTPN21 PTP domain C1108S mutant | 分子名称: | IODIDE ION, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 21 | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | 登録日 | 2022-09-15 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity. Sci Adv, 10, 2024
|
|
8ECG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ecg by Molmil](/molmil-images/mine/8ecg) | Complex of HMG1 with pitavastatin | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, GLYCEROL, Pitavastatin | 著者 | Haywood, J, Bond, C.S. | 登録日 | 2022-09-01 | 公開日 | 2022-09-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action. Nat Commun, 13, 2022
|
|
8GXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxe by Molmil](/molmil-images/mine/8gxe) | PTPN21 FERM PTP complex | 分子名称: | CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21 | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | 登録日 | 2022-09-19 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity. Sci Adv, 10, 2024
|
|
6N4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n4d by Molmil](/molmil-images/mine/6n4d) | The crystal structure of neuramindase from A/canine/IL/11613/2015 (H3N2) influenza virus. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yang, H, Stevens, J. | 登録日 | 2018-11-19 | 公開日 | 2019-01-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States. J. Infect. Dis., 216, 2017
|
|
5ULG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ulg by Molmil](/molmil-images/mine/5ulg) | |
4WST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wst by Molmil](/molmil-images/mine/4wst) | The crystal structure of hemagglutinin from A/Taiwan/1/2013 influenza virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Yang, H, Carney, P.J, Chang, J, Villanueva, J.M, Stevens, J. | 登録日 | 2014-10-28 | 公開日 | 2015-02-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes. J.Virol., 89, 2015
|
|