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8ECG

Complex of HMG1 with pitavastatin

Replaces:  7ULM
Summary for 8ECG
Entry DOI10.2210/pdb8ecg/pdb
Related7ULI
Descriptor3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, GLYCEROL, Pitavastatin, ... (4 entities in total)
Functional Keywordsoxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological sourceArabidopsis thaliana (thale cress)
Total number of polymer chains1
Total formula weight51166.07
Authors
Haywood, J.,Bond, C.S. (deposition date: 2022-09-01, release date: 2022-09-14, Last modification date: 2023-10-18)
Primary citationHaywood, J.,Breese, K.J.,Zhang, J.,Waters, M.T.,Bond, C.S.,Stubbs, K.A.,Mylne, J.S.
A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action.
Nat Commun, 13:5563-5563, 2022
Cited by
PubMed: 36137996
DOI: 10.1038/s41467-022-33185-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.13 Å)
Structure validation

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