6J1U

influenza virus nucleoprotein with a specific inhibitor

Summary for 6J1U

• Entry DOI: 10.2210/pdb6j1u/pdb
• Descriptor: Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide (2 entities in total)
• Functional Keywords: inhibitor, complex, influenza, h1n1, viral protein
• Biological source: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
• Total number of polymer chains: 3
• Total formula weight: 170655.87

Authors

Pang, B.,Zhang, W.Z.,Zhang, H.M.,Hao, Q. (deposition date: 2018-12-29, release date: 2020-01-01, Last modification date: 2023-11-22)

• Primary citation: Yang, F.,Pang, B.,Lai, K.K.,Cheung, N.N.,Dai, J.,Zhang, W.,Zhang, J.,Chan, K.H.,Chen, H.,Sze, K.H.,Zhang, H.,Hao, Q.,Yang, D.,Yuen, K.Y.,Kao, R.Y.; Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle.; J.Virol., 95:-, 2021; PubMed: 33627391; DOI: 10.1128/JVI.01432-20

Experimental method

X-RAY DIFFRACTION (2.8 Å)